60640-97-3Relevant articles and documents
Stilbenoids from Tragopogon orientalis
Zidorn, Christian,Grass, Sandra,Ellmerer, Ernst P.,Ongania, Karl-Hans,Stuppner, Hermann
, p. 2182 - 2188 (2006)
A phytochemical investigation of Tragopogon orientalis L. (Asteraceae, Cichorieae) yielded the natural products 6″-O-(7,8-dihydrocaffeoyl)-α,β-dihydrorhaponticin, 3′-O-methyl-α,β-dihydrorhaponticin, and (S)-3-(4-β-glucopyranosyloxybenzyl)-7-hydroxy-5-meth
Spasmolytic Effects, Mode of Action, and Structure-Activity Relationships of Stilbenoids from Nidema boothii
Hernandez-Romero, Yanet,Rojas, Juana-Isela,Castillo, Rafael,Rojas, Alejandra,Mata, Rachel
, p. 160 - 167 (2007/10/03)
A CH2Cl2-MeOH (1:1) extract prepared from the whole plant of Nidema boothii inhibited spontaneous contractions (IC50 = 6.26 ± 2.5 μg/mL) of the guinea-pig ileum. Bioassay-guided fractionation of the active extract led to t
Antioxidant constituents from rhubarb: Structural requirements of stilbenes for the activity and structures of two new anthraquinone glucosides
Matsuda, Hisashi,Morikawa, Toshio,Toguchida, Iwao,Park, Ji-Young,Harima, Shoichi,Yoshikawa, Masayuki
, p. 41 - 50 (2007/10/03)
The methanolic extracts from five kinds of rhubarb were found to show scavenging activity for DPPH radical and ·O2-. Two new anthraquinone glucosides were isolated from the rhizome of Rheum undulatum L. together with two anthraquinone glucosides, a naphthalene glucoside, and 10 stilbenes. In the screening test for radical scavenging activity of rhubarb constituents, stilbenes and a naphthalene glucoside showed activity, but anthraquinones and sennosides did not. In addition, most stilbenes inhibited lipid peroxidation of erythrocyte membrane by tert-butyl hydroperoxide. Detailed examination of the scavenging effect on various related compounds suggested the following structural requirements; 1) phenolic hydroxyl groups are essential to show the activity; 2) galloyl moiety enhances the activity; 3) glucoside moiety reduces the activity; 4) dihydrostilbene derivatives maintain the scavenging activity for the DPPH radical, but they show weak activity for ·O2-. In addition, several stilbenes with both the 3-hydroxyl and 4′-methoxyl groups inhibited xanthine oxidase.