607832-91-7

Basic information

• Product Name: 2-(3-aMinophenyl)-3-Mercaptopropanoic acid
• Synonyms: 2-(3-aMinophenyl)-3-Mercaptopropanoic acid;WOYCAJIRNXWVLG-UHFFFAOYSA-N
• CAS NO: 607832-91-7
• Molecular Formula: C₉H₁₁NO₂S
• Molecular Weight: 197.25414
• Mol File: 607832-91-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3-aMinophenyl)-3-Mercaptopropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-aMinophenyl)-3-Mercaptopropanoic acid(607832-91-7)
• EPA Substance Registry System: 2-(3-aMinophenyl)-3-Mercaptopropanoic acid(607832-91-7)

Safety Data

• Hazardous Substances Data: 607832-91-7(Hazardous Substances Data)

Upstream product

• 934477-00-6 3-acetylsulfanyl-2-(3-tert-butoxycarbonylamino-phenyl)-propionic acid 
• 200214-35-3 3-(Boc-amino)phenylacetic acid ethyl ester 
• 934476-98-9 2-(3-tert-butoxycarbonylamino-phenyl)-acrylic acid 
• 607835-01-8 2-(3-tert-butoxycarbonylamino-phenyl)-acrylic acid ethyl ester 

Downstream Products

• 607833-29-4 2-(3-guanidinophenyl)-3-mercaptopropanoic acid 

Relevant articles and documents

3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa)

A novel series of cyclic potent, selective, small molecule, thiol-based inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa) and the crystal structures of TAFIa inhibitors bound to porcine pancreatic carboxypeptidase B are described. Three series of cyclic arginine and lysine mimetic inhibitors vary significantly in their selectivity against other human basic carboxypeptidases, carboxypeptidase N and carboxypeptidase B. (-)2a displays TAFIa IC50 = 3 nM and 600-fold selectivity against CPN. Inhibition of TAFIa with (rac)2a resulted in dose dependent acceleration of human plasma clot lysis in vitro and was efficacious as an adjunct to tPA in an in vivo rabbit jugular vein thrombolysis model.