60989-80-2

Basic information

• Product Name: 1,4-Butanediol, 2-(phenylmethoxy)-, (2S)-
• CAS NO: 60989-80-2
• Molecular Formula: C11H16O3
• Molecular Weight: 196.246
• Mol File: 60989-80-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,4-Butanediol, 2-(phenylmethoxy)-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Butanediol, 2-(phenylmethoxy)-, (2S)-(60989-80-2)
• EPA Substance Registry System: 1,4-Butanediol, 2-(phenylmethoxy)-, (2S)-(60989-80-2)

Safety Data

• Hazardous Substances Data: 60989-80-2(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 82130-73-2 dimethyl (S)-(-)-2-benzyloxybutanedioate 
• 1337562-41-0 (S)-2-benzyloxy-1-(3,4-dimethoxybenzyloxy)-4-(4-methoxybenzyloxy)butane 
• 101999-38-6 (S)-4-benzyloxy-dihydrofuran-2(3H)-one 
• 554427-68-8 2-(tert-butyl-diphenyl-silanyloxy)-succinic acid dimethyl ester 
• 691-84-9 Diethyl (S)-malate 

Downstream Products

• 1185984-56-8 C₁₃H₂₀O₇S₂ 
• 554427-73-5 (S)-(((1,4-diiodobutan-2-yl)oxy)methyl)benzene 
• 1415118-36-3 (1S,3S)-3-(benzyloxy)-1-(p-tolyl)cyclopentanecarbonitrile 
• 1415118-41-0 (1R,3S)-3-(benzyloxy)-1-(p-tolyl)cyclopentanecarbonitrile 
• 1415118-38-5 1-((1R,3S)-3-(benzyloxy)-1-methylcyclopentyl)-4-methylbenzene 
• 1415118-43-2 1-((1S,3S)-3-(benzyloxy)-1-methylcyclopentyl)-4-methylbenzene 
• 1067244-44-3 (S)-O-benzyl-3,5-dioxacycloheptan-1-ol 
• 60989-81-3 2(S)-(Benzyloxy)-1,4-bis(tosyloxy)butane 
• 32233-43-5 2-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanol 

Relevant articles and documents

Preparation method of (S)-3-hydroxytetrahydrofuran

The invention discloses a preparation method of (S)-3-hydroxytetrahydrofuran. The problems that butantriol is difficult to separate in the production process, the yield is not high and the impurity content and the isomer content of the products are high are mainly solved. The preparation method of (S)-3-hydroxytetrahydrofuran comprises the following steps: under the existence of sulfoxide chloride, malic acid reacts with methanol to generate a compound II; under the existence of silver oxide, performing reaction on the compound II and benzyl bromide to generate a compound III; reducing the compound III by sodium borohydride to generate a compound IV; performing dehydration and ring closing on the compound IV by p-toluenesulfonic acid to generate a compound V; and taking palladium carbon asa catalyst and performing hydrogen reduction treatment on the compound V to obtain the product. The method is simple in aftertreatment and environment-friendly; the yield of the products is increasedby 80 percent or more, the purity is more than 99.5 percent and the chiral purity is more than 99.2 percent; and the method is suitable for industrialized production. (The formulas are as shown in the description).

A chiral pool based approach to antipodes of α-cuparenone

A synthetic route to both antipodes of α-cuparenone was achieved from the readily available chiral pool starting material l-malic acid and involved cyclopentannulation as the key step.

Effective chemoselective deprotection of 3,4-dimethoxybenzyl ( 3,4DMB) ethers in the presence of benzyl and p-methoxybenzyl (PMB) ethers by phenyliodine(III) bis(trifluoroacetate) (PIFA)

In this Letter, a selective deprotection of the alcohol protecting 3,4-dimethoxybenzyl (3,4DMB) group is described. The hypervalent iodine(III) reagent phenyliodine bis(trifluoroacetate) (PIFA) is found to be an efficient reagent for the chemos