6117-16-4

Basic information

• Product Name: 4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester
• Synonyms: 4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester
• CAS NO: 6117-16-4
• Molecular Weight: 204.228
• Mol File: 6117-16-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester(6117-16-4)
• EPA Substance Registry System: 4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid methyl ester(6117-16-4)

Safety Data

• Hazardous Substances Data: 6117-16-4(Hazardous Substances Data)

Upstream product

• 186581-53-3 diazomethane 
• 103-26-4 Methyl cinnamate 
• 80-11-5 N-methyl-N-nitrosotoluene-p-sulfonamide 
• 103-26-4 methyl cinnamate 
• 140-10-3 (E)-3-phenylacrylic acid 

Downstream Products

• 46160-01-4 trans-3-amino-4-phenylpyrrolidin-2-one 
• 46160-01-4 cis-3-amino-4-phenylpyrrolidin-2-one 

Relevant articles and documents

CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND

A process for producing a reaction product of a diazo compound, which process comprises: a. continuously supplying to a first reactor a precursor of a diazo compound; a water-miscible solvent; a base and water; b. mixing the precursor of a diazo compound; the water-miscible solvent; the base and water to generate a diazo compound; c. continuously removing from the first reactor, through a hydrophobic membrane, into a second reactor the formed diazo compound; d. continuously removing from the first reactor all reaction products that have not passed into the second reactor; e. continuously supplying to the second reactor a substrate in a non-water-miscible solvent; f. mixing the above components to generate a reaction product of a diazo compound; and g. continuously removing from the second reactor the non-water-miscible solvent and the reaction product of the diazo compound, and apparatus suitable for carrying out such a process.

MITOTIC KINESIN INHIBITORS

The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to composition