61340-33-8Relevant articles and documents
Azo high polymer for transporting medicine to intestinal tracts and releasing medicine as well as preparation method and application of azo high polymer
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Paragraph 0030; 0034-0036, (2021/08/21)
The invention discloses an azo high polymer for transporting medicine to intestinal tracts and releasing the medicine as well as a preparation method and application of the azo high polymer. The azo high polymer is synthesized by taking dibromoalkane with two brominated ends, oligomeric glycol, paranitroaniline and m-hydroxybenzoic acid as main raw materials. The final structure of the azo high polymer is shown in a formula described in the specifications of the invention; in the formula, x is equal to the sum of y and z, n is equal to 2, 3, 4, 5..., m is equal to 2, 3, 4, 5...; the high polymer can wrap the medicine to form particles through a double emulsification method, the particles reach the intestinal tracts through oral administration, then azo bonds are cut off by bacteria living in the intestinal tracts, the medicine is released, and therefore the effect of treating intestinal diseases is achieved.