6136-93-2 Usage
Description
Diethoxyacetonitrile, a 2,2-dialkoxyalkanenitrile derivative, is a chemical compound synthesized through the reaction of hydrocyanic acid with various ortho esters of aliphatic and aromatic acids in the presence of an acidic catalyst. It is known for its involvement in the Houben-Hoesch reaction, which results in the formation of tris(2,4,5-trimethoxyphenyl)methane.
Uses
Used in Chemical Synthesis:
Diethoxyacetonitrile is used as a key intermediate in the synthesis of various organic compounds. Its reactivity and versatility make it a valuable component in the production of different chemical products.
Used in Pharmaceutical Industry:
Diethoxyacetonitrile is used as a starting material for the preparation of methyl 5-diethoxymethylimidazole-4-carboxylate, which is achieved through an anionic cycloaddition reaction with methyl isocyanoacetate. DIETHOXYACETONITRILE has potential applications in the development of pharmaceuticals, particularly those targeting specific biological pathways.
Used in Organic Chemistry Research:
Due to its unique structure and reactivity, diethoxyacetonitrile is also utilized in organic chemistry research to explore new reaction pathways, develop novel synthetic methods, and create innovative molecular structures with potential applications in various fields, including materials science, pharmaceuticals, and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 6136-93-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,3 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6136-93:
(6*6)+(5*1)+(4*3)+(3*6)+(2*9)+(1*3)=92
92 % 10 = 2
So 6136-93-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO2/c1-3-8-6(5-7)9-4-2/h6H,3-4H2,1-2H3
6136-93-2Relevant articles and documents
Metal-Free Oxidation of Primary Amines to Nitriles through Coupled Catalytic Cycles
Lambert, Kyle M.,Bobbitt, James M.,Eldirany, Sherif A.,Kissane, Liam E.,Sheridan, Rose K.,Stempel, Zachary D.,Sternberg, Francis H.,Bailey, William F.
supporting information, p. 5156 - 5159 (2016/04/09)
Synergism among several intertwined catalytic cycles allows for selective, room temperature oxidation of primary amines to the corresponding nitriles in 85-98 % isolated yield. This metal-free, scalable, operationally simple method employs a catalytic quantity of 4-acetamido-TEMPO (ACT; TEMPO=2,2,6,6-tetramethylpiperidine N-oxide) radical and the inexpensive, environmentally benign triple salt oxone as the terminal oxidant under mild conditions. Simple filtration of the reaction mixture through silica gel affords pure nitrile products.
NOVEL MINOR GROOVE BINDERS
-
Page/Page column 63-64, (2008/06/13)
There is provided compounds of formula (I), wherein R1, R11, R12, Qa, X, Qb, Qc, A and D have meanings given in the description, or a pharmaceutically acceptable salt or solvate thereof, which compound, salt or solvate binds to the minor groove of DNA.
Total synthesis of antibiotic althiomycin
Inami,Shiba
, p. 352 - 360 (2007/10/02)
-