61416-34-0

Basic information

• Product Name: 2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE
• Synonyms: 2-AMINO-1-(3,4-DIMETHOXY-PHENYL)-ETHANONE HYDROCHLORIDE;2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE;2-AMino-1-(3,4-diMethoxyphenyl)-1-ethanone HCl;2-Amino-3',4'-dimethoxyacetophenone hydrochloride;2-(3,4-dimethoxyphenyl)-2-oxoethan-1-aminium chloride
• CAS NO: 61416-34-0
• Molecular Formula: C₁₀H₁₃NO₃*ClH
• Molecular Weight: 231.68
• Mol File: 61416-34-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE(61416-34-0)
• EPA Substance Registry System: 2-(3,4-DIMETHOXY-PHENYL)-2-OXO-ETHYL-AMMONIUM, CHLORIDE(61416-34-0)

Safety Data

• Hazardous Substances Data: 61416-34-0(Hazardous Substances Data)

Usage

Preparation

Also obtained by treatment of a-bromo-3,4-dimethoxyacetophenone with hexamethylenetetramine in chloroform at r.t. for 1 h.

InChI:InChI=1/C10H13NO3.ClH/c1-13-9-4-3-7(8(12)6-11)5-10(9)14-2;/h3-5H,6,11H2,1-2H3;1H

Upstream product

• 100-97-0 hexamethylenetetramine 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 871902-52-2 N-(3,4-dimethoxy-phenacyl)-phthalamic acid 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 

Downstream Products

• 90253-94-4 2-(Isobutyrylamino)-3',4'-dimethoxyacetophenon 
• 90253-95-5 5-(3,4-Dimethoxyphenyl)-2-isopropyloxazol 
• 90253-91-1 7-(3,4-Dimethoxybenzoyl)-5-isopropyl-2-phenyl-1H,7H-s-triazolo<1,2-a>-s-triazol-1,3(2H)-dion 
• 932750-20-4 5-amino-1-cyclopentyl-N-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-3-ethyl-1H-pyrazole-4-carboxamide 
• 877387-19-4 C₂₀H₂₂N₂O₆ 
• 877386-95-3 C₃₀H₃₃N₃O₁₀ 
• 5190-84-1 2-(Acetylamino)-3',4'-dimethoxyacetophenon 

Relevant articles and documents

Synthesis of 2-Amino Substituted Oxazoles from α-Amino Ketones and Isothiocyanates via Sequential Addition and I2-Mediated Desulfurative Cyclization

Oxazol-2-amines were synthesized by annulation of α-amino ketones and isothiocyanates. This sequential synthetic process involves addition of α-amino ketones to isothiocyanates and I2-promoted desulfurative cyclization omitting isolation of the less stable thiourea intermediates. It is transition metal-free and operationally simple, providing access to a variety of 2-amino substituted oxazole derivatives under mild reaction conditions. (Figure presented.).

NOVEL 5,6-DIHYDROPYRAZOLO[3,4-E] [L,4]DIAZEPIN-4 (IH) -ONE DERIVATIVES FOR THE TREATMENT OF ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE.

The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a PDE 4 mediated disease state.