61424-26-8

Basic information

• Product Name: 3-BENZYLANILINE
• Synonyms: 3-BENZYLANILINE;[3-(benzyl)phenyl]amine;3-(phenylmethyl)aniline;3-Benzylaniline 97%;3-Benzylbenzenamine;NSC 210972
• CAS NO: 61424-26-8
• Molecular Formula: C₁₃H₁₃N
• Molecular Weight: 183.25
• Product Categories: Amines;C11 to C38;Nitrogen Compounds
• Mol File: 61424-26-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 48-52 °C(lit.)
• Boiling Point: 126°C 2mm
• Flash Point: 112 °F
• Appearance: solid
• Density: 1.07 g/cm³
• Vapor Pressure: 0.000205mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: 2-8°C
• PKA: 4.67±0.10(Predicted)
• BRN: 2803261
• CAS DataBase Reference: 3-BENZYLANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYLANILINE(61424-26-8)
• EPA Substance Registry System: 3-BENZYLANILINE(61424-26-8)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36
• RIDADR: UN 1325 4.1/PG 3
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 61424-26-8(Hazardous Substances Data)

Usage

General Description

3-Benzylaniline is a chemical compound with the formula C13H11N. It is an organic compound that is commonly used as an intermediate in the synthesis of various pharmaceuticals and dyes. It is a white solid at room temperature and is slightly soluble in water. 3-Benzylaniline is also used as a building block in the production of other organic compounds and is commonly found in research and industrial laboratories. It is important to handle this chemical with care as it is a potential irritant to the eyes and skin.

InChI:InChI=1/C13H13N/c14-13-8-4-7-12(10-13)9-11-5-2-1-3-6-11/h1-8,10H,9,14H2

Upstream product

• 5840-41-5 1-benzyl-3-nitrobenzene 
• 2243-80-3 3-nitrobenzophenone 
• 141883-38-7 2-chloro-5-nitro-benzophenone oxime 
• 7647-01-0 hydrogenchloride 
• 619-25-0 3-Nitrobenzyl alcohol 
• 71-43-2 benzene 
• 619-23-8 3-Nitrobenzyl chloride 
• 2835-78-1 3-amino benzophenone 
• 108-42-9 3-chloro-aniline 
• 100-44-7 benzyl chloride 

Downstream Products

• 63021-27-2 acetic acid-(3-benzyl-anilide) 
• 55251-23-5 3-Benzyltrifluoromethanesulfonanilid 
• 120454-32-2 2-benzylphenyl O-ethyl dithiocarbonate 
• 24796-14-3 2-[(3-Benzyl-phenylamino)-methylene]-malonic acid diethyl ester 
• 1004539-86-9 S-3-benzylphenyl-O-ethyl carbonodithioate 
• 169797-54-0 3-benzylthiophenol 
• 944705-78-6 3-(3-benzylphenylthio)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide 
• 261-31-4 thioxanthene 

Relevant articles and documents

One-pot borylation/Suzuki-Miyaura sp2-sp3 cross-coupling

We describe the first one-pot borylation/Suzuki-Miyaura sp2-sp3 cross-coupling between readily available aryl (pseudo)halides and activated alkyl chlorides. This method streamlines the synthesis of diaryl methanes, α-aryl carbonyls and allyl aryl compounds, substructures that are commonly found in life changing drug molecules.

Novel SIRT2 protein inhibitor and usage thereof in pharmacy

The invention discloses a compound or salt, crystallographic form and solvate compounds of the compound acceptable in pharmacy, and the compound and the salt, crystallographic form, solvate compounds of the compound are shown as formula I, wherein X is selected from the formulas (please see the specifications for the formula); R1 is selected from aryl or ceteroary or substituted aryl or substituted ceteroary or from the formula (please see the specifications for the formula); R2 is selected from the formulas (please see the specifications for the formula); and R3 is selected from halogen or C1-C4 alkyl or C1-C4 alkoxy. The novel compound shown in formula I has the advantages that not only is good inhibitory activity achieved to SIRT2, but also the inhibiting effect is achieved to the tumor, and the novel compound has good pharmaceutical potentiality and provides a novel potential choice for the clinical medicament.

MILD AND SIMPLE HYDROGENATION OF DIARYL OXIMES TO HYDROCARBONS USING AMMONIUM FORMATE-PALLADIUM ON CARBON

Various diaryl ketoximes have been reduced to the corresponding hydrocarbons under mild conditions using ammonium formate as the hydrogen source.