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61453-48-3

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61453-48-3 Usage

General Description

Ethyl 5-(hydroxymethyl)-1H-pyrazole-3-carboxylate is a chemical compound with the molecular formula C8H12N2O4. It is a derivative of pyrazole, containing an ethyl ester group, a carboxylic acid group, and a hydroxymethyl group. ethyl 5-(hydroxymethyl)-1H-pyrazole-3-carboxylate has potential applications in organic synthesis and pharmaceutical research. It may also have biological activity due to its structural similarity to other pyrazole derivatives, which are known to have various pharmacological properties. Due to its specific structure and properties, ethyl 5-(hydroxymethyl)-1H-pyrazole-3-carboxylate has the potential to be utilized in a range of scientific and industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 61453-48-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,4,5 and 3 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 61453-48:
(7*6)+(6*1)+(5*4)+(4*5)+(3*3)+(2*4)+(1*8)=113
113 % 10 = 3
So 61453-48-3 is a valid CAS Registry Number.

61453-48-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 5-(hydroxymethyl)-1H-pyrazole-3-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61453-48-3 SDS

61453-48-3Relevant articles and documents

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Akhrem et al.

, (1976)

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BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF

-

Page/Page column 65; 66, (2019/02/02)

The invention provides novel compounds having the general formula (I): (I) wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.

Agonist lead identification for the high affinity niacin receptor GPR109a

Gharbaoui, Tawfik,Skinner, Philip J.,Shin, Young-Jun,Averbuj, Claudia,Jung, Jae-Kyu,Johnson, Benjamin R.,Duong, Tracy,Decaire, Marc,Uy, Jane,Cherrier, Martin C.,Webb, Peter J.,Tamura, Susan Y.,Zou, Ning,Rodriguez, Nathalie,Boatman, P. Douglas,Sage, Carleton R.,Lindstrom, Andrew,Xu, Jerry,Schrader, Thomas O.,Smith, Brian M.,Chen, Ruoping,Richman, Jeremy G.,Connolly, Daniel T.,Colletti, Steven L.,Tata, James R.,Semple, Graeme

, p. 4914 - 4919 (2008/02/12)

A strategy for lead identification of new agonists of GPR109a, starting from known compounds shown to activate the receptor, is described. Early compound triage led to the formulation of a binding hypothesis and eventually to our focus on a series of pyrazole acid derivatives. Further elaboration of these compounds provided a series of 5,5-fused pyrazoles to be used as lead compounds for further optimization.

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