618889-20-6

Basic information

• Product Name: 3-amino-1-(ethanoyl)-6-chloro-1H-indole-2-carboxylic acid ethyl ester
• CAS NO: 618889-20-6
• Molecular Weight: 280.711
• Mol File: 618889-20-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-amino-1-(ethanoyl)-6-chloro-1H-indole-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-1-(ethanoyl)-6-chloro-1H-indole-2-carboxylic acid ethyl ester(618889-20-6)
• EPA Substance Registry System: 3-amino-1-(ethanoyl)-6-chloro-1H-indole-2-carboxylic acid ethyl ester(618889-20-6)

Safety Data

• Hazardous Substances Data: 618889-20-6(Hazardous Substances Data)

Upstream product

• 53312-91-7 N-(5-chloro-2-cyanophenyl)acetamide 
• 40258-78-4 1-bromoethyl acetate 

Downstream Products

• 210571-49-6 ethyl 3-amino-6-chloro-1H-indole-2-carboxylate 

Relevant articles and documents

Interleukin-4 gene expression inhibitors

This invention discloses and claims a class of indole and benzo(b)thiophene derivatives for use in treating allergy, asthma, rhinitis, dermatitis, B-cell lymphomas, tumors and diseases associated with bacterial, rhinovirus or respiratory syncytial virus (RSV) infections. The compounds of this invention are defined by the Formula (I): wherein X, Y, Z, R1, R2 and R3 are as defined in the specification; or a pharmaceutically acceptable salt thereof. In preferred embodiments of this invention it is also disclosed and claimed that the compounds of this invention are capable of modulating T helper (Th) cells, Th1/Th2, and thereby capable of inhibiting the transcription of interleukin-4 (IL-4) message, IL-4 release or IL-4 production.