619-03-4

Basic information

• Product Name: 3,4-DIBROMOBENZOIC ACID
• Synonyms: 3,4-DIBROMOBENZOIC ACID;RARECHEM AL BE 1504
• CAS NO: 619-03-4
• Molecular Formula: C₇H₄Br₂O₂
• Molecular Weight: 279.91
• Product Categories: Acids & Esters;Bromine Compounds
• Mol File: 619-03-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 235-236 °C
• Boiling Point: 356°C at 760 mmHg
• Flash Point: 169.1°C
• Appearance: /
• Density: 2.083g/cm³
• Vapor Pressure: 1.1E-05mmHg at 25°C
• Refractive Index: 1.642
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.58±0.10(Predicted)
• CAS DataBase Reference: 3,4-DIBROMOBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIBROMOBENZOIC ACID(619-03-4)
• EPA Substance Registry System: 3,4-DIBROMOBENZOIC ACID(619-03-4)

Safety Data

• Hazardous Substances Data: 619-03-4(Hazardous Substances Data)

Usage

General Description

3,4-Dibromobenzoic acid is a compound with the chemical formula C7H4Br2O2. It is a white crystalline solid that is used in various chemical and pharmaceutical applications. This chemical is often used as a building block in the synthesis of more complex organic compounds. It is also used in the production of dyes, pigments, and as an intermediate in the synthesis of rubber and plastic additives. Additionally, 3,4-Dibromobenzoic acid is a useful starting material for the synthesis of pharmaceutical drugs, particularly in the development of anti-inflammatory and analgesic medications.

InChI:InChI=1/C7H4Br2O2/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3H,(H,10,11)

Upstream product

• 2840-29-1 3-amino-4-bromobenzoic acid 
• 7732-18-5 water 
• 7726-95-6 bromine 
• 65-85-0 benzoic acid 
• 60956-23-2 3,4-dibromotoluene 
• 64-19-7 acetic acid 
• 98-08-8 α,α,α-trifluorotoluene 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 247045-28-9 4,5-dibromophthalimide 
• 106-38-7 para-bromotoluene 
• 1122-91-4 4-bromo-benzaldehyde 
• 163596-75-6 4-bromo-3-nitrobenzaldehyde 
• 99-90-1 para-bromoacetophenone 
• 401-75-2 trifluoromethylcyclohexane 

Downstream Products

• 21900-35-6 3,4-dibromobenzoyl chloride 
• 102000-63-5 4,5-dibromo-2-nitro-benzoic acid 
• 60469-88-7 1,2-dibromo-4-(ethoxycarbonyl)benzene 
• 68119-98-2 1,2-dibromo-4-(hydroxymethyl)benzene 
• 96238-00-5 1-(3,4-dibromobenzoyl)-2-(p-nitrobenzoyl)hydrazine 
• 75057-62-4 2-amino-4,5-dibromobenzoic acid 

Relevant articles and documents

Substitution Reactions of Phenylated Aza-Heterocycles. Part 2. Bromination of Some 2,5-Diaryl-1,3,4-oxadiazoles

Electrophilic bromination of the title compounds may be achieved using either bromine in oleum, or bromine and potassium bromate in a sulphuric-acetic acid mixture.Under the milder reaction conditions provided by the latter, 2-(p-nitrophenyl)-5-phenyl-1,3,4-oxadiazole (2), the model compound used in this study, is mono- and di-brominated in the phenyl ring.In the first bromination step, all three monobromo-isomers are produced in appreciable amount.The orientation of the second bromination is controlled entirely by the first bromine and not by the oxadiazole substituent: this is confirmed by a separate study of the bromination of the three monobromo-compounds (3a-3c).

Use of Potassium Bromate: Bromination of Halobenzenes and Halobenzoic Acids

Syntheses of bromo compounds by the bromination of halobenzenes and halobenzoic acids using potassium bromate under acidic condition have been discussed.