619-91-0

Basic information

• Product Name: (4-Nitroanilino)acetic acid
• Synonyms: (4-Nitroanilino)acetic acid;N-(4-Nitrophenyl)glycine;N-(p-Nitrophenyl)glycine;p-Nitroanilinoacetic acid;2-[(4-Nitrophenyl)amino]acetic acid
• CAS NO: 619-91-0
• Molecular Formula: C₈H₈N₂O₄
• Molecular Weight: 196.16
• Mol File: 619-91-0.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 333.03°C (rough estimate)
• Flash Point: 234.5°C
• Appearance: /
• Density: 1.4290 (rough estimate)
• Vapor Pressure: 2.06E-09mmHg at 25°C
• Refractive Index: 1.6180 (estimate)
• CAS DataBase Reference: (4-Nitroanilino)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Nitroanilino)acetic acid(619-91-0)
• EPA Substance Registry System: (4-Nitroanilino)acetic acid(619-91-0)

Safety Data

• Hazardous Substances Data: 619-91-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8N2O4/c11-8(12)5-9-6-1-3-7(4-2-6)10(13)14/h1-4,9H,5H2,(H,11,12)

Upstream product

• 127-09-3 sodium acetate 
• 100-01-6 4-nitro-aniline 
• 79-11-8 chloroacetic acid 
• 350-46-9 4-Fluoronitrobenzene 
• 56-40-6 glycine 
• 90544-84-6 N-formyl-N-(4-nitro-phenyl)-glycine 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 7732-18-5 water 
• 105-36-2 ethyl bromoacetate 
• 79-08-3 bromoacetic acid 
• 586-78-7 para-nitrophenyl bromide 
• 298-12-4 Glyoxilic acid 

Downstream Products

• 103028-70-2 3-(4-nitro-phenyl)-oxazolidine-2,5-dione 
• 2835-08-7 N-(4-aminophenyl)glycine 
• 69978-02-5 N-(4-nitro-phenyl)-N-nitroso-glycine 
• 90544-88-0 N-4-nitrophenylglycine methyl ester 
• 14606-04-3 4-bromo-3-(4-nitrophenyl)-1,2,3λ⁵-oxadiazol-3-ylium-5-olate 
• 773844-67-0 N-4-methanesulfonylamino-phenylglycine 
• 851680-27-8 N-4-propanesulfonylamino-phenylglycine 
• 851680-24-5 [(4-Amino-phenyl)-(2,2,2-trifluoro-acetyl)-amino]-acetic acid methyl ester 
• 851680-23-4 [(4-Nitro-phenyl)-(2,2,2-trifluoro-acetyl)-amino]-acetic acid methyl ester 
• 851680-25-6 [(4-(Bismethanesulfonyl)amino-phenyl)-(2,2,2-trifluoro-acetyl)-amino]-acetic acid methyl ester 
• 98953-48-1 N-methyl-N-(4-nitrophenyl)glycine 
• 1029803-76-6 ((4-nitrophenyl)(2,2,2-trfluoroacetyl)amino)acetic acid 
• 1095558-01-2 N,N-dimethyl-2-(4-nitrophenylamino)acetamide 
• 17105-35-0 3-(4-aminophenyl)sydnone 

Relevant articles and documents

Mechanosynthesis of sydnone-containing coordination complexes

N-Phenyl-4-(2-pyridinyl) sydnone was shown to act as a four-electron donor N,O-ligand in unprecedented coordination complexes featuring three different metallic centers (Co, Cu, and Zn). Starting with various anilines, the use of a ball-mill efficiently enabled the synthesis of N-arylglycines, subsequent nitrosylation and cyclization into sydnones, and further metalation.

Cu(II)-catalyzed C-N coupling of (hetero)aryl halides and N-Nucleophiles promoted by α-benzoin oxime

We first reported the new application of a translate metal chelating ligand α-benzoin oxime for improving Cu-catalyzed C-N coupling reactions. The system could catalyse coupling reactions of (hetero)aryl halides with a wide of nucleophiles (e.g., azoles, piperidine, pyrrolidine and amino acids) in moderate to excellent yields. The protocol allows rapid access to the most common scaαolds found in FDA-approved pharmaceuticals.

Photo-polymerization properties of type-II photoinitiator systems based on 2-chlorohexaaryl biimidazole (o-Cl-HABI) and various N-phenylglycine (NPG) derivatives

A series of p-substituted NPG derivatives (Cl-NPG, OMe-NPG and NO2-NPG) comprising different push-pull characteristics have been synthesized and characterized. The NPG derivatives have good thermal stability and red shifted absorption when comp