62008-36-0 Usage
Check Digit Verification of cas no
The CAS Registry Mumber 62008-36-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,0,0 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 62008-36:
(7*6)+(6*2)+(5*0)+(4*0)+(3*8)+(2*3)+(1*6)=90
90 % 10 = 0
So 62008-36-0 is a valid CAS Registry Number.
InChI:InChI=1/C50H77NO18/c1-29-19-17-15-13-11-9-7-8-10-12-14-16-18-20-37(68-49-47(62)44(51-33(5)52)46(61)32(4)67-49)26-41-43(48(63)65-6)40(58)28-50(64,69-41)27-36(55)24-39(57)38(56)22-21-34(53)23-35(54)25-42(59)66-31(3)30(2)45(29)60/h7-20,29-32,34-41,43-47,49,53-58,60-62,64H,21-28H2,1-6H3,(H,51,52)/b8-7+,11-9+,12-10-,15-13+,16-14+,19-17+,20-18+
62008-36-0Relevant articles and documents
Retrosynthetic and Synthetic Chemistry on Amphotericin B. Synthesis of C(1)-C(20) and C(21)-C(38) Fragments and Construction of the 38-Membered Macrocycle
Nicolaou, K. C.,Chakraborty, T. K.,Daines, R. A.,Simpkins, N. S.
, p. 413 - 416 (2007/10/02)
For the first time, amphotericin B (I) has been successfully derivatized and degraded to intermediates that have been converted into compounds (II) and (III) , projected as major key intermediates for a total synthesis; methods have been developed for the coupling of fragments (II) and (III) to give the ketophosphonate-aldehyde (28) and for the cyclization of this precursor to the 38-membered macrocyclic heptaenone (29) in 70-80percent yield.
