620949-99-7Relevant articles and documents
Benzimidazole derivatives. Part 5: Design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT 1A/5-HT3 ligands
López-Rodríguez, María L.,Benhamú, Bellinda,Morcillo, Ma José,Tejada, Ignacio,Avila, David,Marco, Isabel,Schiapparelli, Lucio,Frechilla, Diana,Del Río, Joaquín
, p. 5181 - 5191 (2007/10/03)
A series of new mixed benzimidazole-arylpiperazine derivatives were designed by incorporating in general structure III the pharmacophoric elements of 5-HT1A and 5-HT3 receptors. Compounds 1-11 were synthesized and evaluated for bindi