624-82-8 Usage
Uses
Formamidoxime may be used as inhibitor of DNA synthesis.
Biochem/physiol Actions
Formamidoxime undergoes oxidative cleavage of C==N bonds in tracheal smooth muscle cells catalyzed by liver cytochrome P450 producing NO. It inhibits replicative DNA synthesis. It has antitumor activity against L1210 leukemia.
Check Digit Verification of cas no
The CAS Registry Mumber 624-82-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 624-82:
(5*6)+(4*2)+(3*4)+(2*8)+(1*2)=68
68 % 10 = 8
So 624-82-8 is a valid CAS Registry Number.
InChI:InChI=1/CH4N2O/c2-1-3-4/h1,4H,(H2,2,3)
624-82-8Relevant articles and documents
Survey Reactivity of Some Substituted Quinazolinones with Pentafluoro(chloro)pyridine
Ranjbar-Karimi, Reza,Davodian, Tayebeh,Mehrabi, Hossein
, p. 475 - 480 (2017/12/28)
A new series of 4-hetroaryl substituted quinazolines were designed and synthesized by the reaction of pentafluoro(chloro)pyridine and 2-substituted quinazolinone. The aromatic nucleophilic substitution of pentafluoro(chloro)pyridine with quinazolinone occurs at the 4-position of pyridine ring by the oxygen site (O-centered nucleophile) of quinazolinone. The structures of all the compounds were confirmed by IR, 1H NMR, 19F NMR, and 13C NMR spectroscopy as well as elemental analysis.
