62400-75-3 Usage
Description
5-Hydroxymethyl-pyrrolidine-2-one, also known as 5-(hydroxymethyl)-2-pyrrolidinone, is an organic compound that serves as a building block and analog for various applications in the pharmaceutical and chemical industries. It is characterized by its unique chemical structure, which includes a hydroxymethyl group and a pyrrolidine ring, making it a versatile molecule for synthesis and modification.
Uses
Used in Pharmaceutical Industry:
5-Hydroxymethyl-pyrrolidine-2-one is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure allows for the creation of new molecules with potential therapeutic properties, contributing to the development of novel drugs.
Used in Cancer Research:
5-Hydroxymethyl-pyrrolidine-2-one is used as an analog of Pramanicin, a compound that induces apoptosis in human colon cancer cells. Its role in cancer research is significant, as it may help in the development of new treatments for colon cancer and other related malignancies.
Used in Stereochemistry:
5-Hydroxymethyl-pyrrolidine-2-one is also available with specified stereochemistry, which is crucial for its application in the synthesis of chiral molecules. The stereochemistry of this compound can be tailored to meet specific requirements in the pharmaceutical and chemical industries, enhancing its utility in the development of enantiomerically pure compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 62400-75-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,4,0 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 62400-75:
(7*6)+(6*2)+(5*4)+(4*0)+(3*0)+(2*7)+(1*5)=93
93 % 10 = 3
So 62400-75-3 is a valid CAS Registry Number.
62400-75-3Relevant articles and documents
FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF
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, (2017/05/14)
The present disclosure relates to Fused Morpholinopyrimidines, pharmaceutical compositions comprising an effective amount of a Fused Morpholinopyrimidine and methods for using a Fused Morpholinopyrimidine in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of a Fused Morpholinopyrimidine.
FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF
-
, (2015/08/03)
The present disclosure relates to Fused Morpholinopyrimidines, pharmaceutical compositions comprising an effective amount of a Fused Morpholinopyrimidine and methods for using a Fused Morpholinopyrimidine in the treatment of a neurodegenerative disease, comprising administering to a subject in need thereof an effective amount of a Fused Morpholinopyrimidine.
Tethered aminohydroxylation (TA) reaction of amides
Donohoe, Timothy J.,Callens, Cedric K. A.,Thompson, Amber L.
supporting information; experimental part, p. 2305 - 2307 (2009/10/23)
The first examples of amide-tethered aminohydroxylation reactions, catalyzed by osmium, showing that the use of N-O-based reoxidants are essential for success, are reported. The system that is described is compatible with a variety of different alkene sub
