62547-34-6

Basic information

• Product Name: Benzoic acid, 5-chloro-3-(chlorosulfonyl)-2-hydroxy-
• CAS NO: 62547-34-6
• Molecular Formula: C7H4Cl2O5S
• Molecular Weight: 271.078
• Mol File: 62547-34-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 5-chloro-3-(chlorosulfonyl)-2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 5-chloro-3-(chlorosulfonyl)-2-hydroxy-(62547-34-6)
• EPA Substance Registry System: Benzoic acid, 5-chloro-3-(chlorosulfonyl)-2-hydroxy-(62547-34-6)

Safety Data

• Hazardous Substances Data: 62547-34-6(Hazardous Substances Data)

Upstream product

• 321-14-2 5-chloro-2-hydroxybenzoic acid 

Downstream Products

• 68029-67-4 5,5'-dichloro-2,2'-dihydroxy-3,3'-disulfanediyl-di-benzoic acid 
• 3510-48-3 4-chlorobenzaldehyde azine 
• 2299-73-2 N,N-bis(4-methoxybenzylidene)hydrazine 
• 80414-89-7 5-chlorosalicylic acid-3-sulfonyl azide 
• 80414-86-4 3-Hydrazinosulfonyl-5-chlorosalicylic acid 

Relevant articles and documents

ACLY INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of ATP citrate lyase (ACLY), compositions thereof, and methods of using the same.

SALICYLIC ACID SULFONYL DERIVATIVES AND RELATED COMPOUNDS

Salicylic acid-5-sulfonohydrazide (3) has been condensed with β-dicarbonyl compounds to form pyrazoles (5).With ethyl acetoacetate, tri- and hexafluoropentane-2,4-dione the hydrazones (4) were obtained; although the former did cyclise in the presence of potassium carbonate-magnesium sulfate.With hexane-2,5-dione the pyrrole (7) was formed and not the pyridazine (8).Acylation of salicylic acid-5- and p-acetamidobenzene-sulfonohydrazides was examined; mono-acetates, benzoates and p-toluenesulfonates and diacetates are described, but other pure diacyl derivatives could not be i solated.Reaction with succinic and maleic anhydrides gave the corresponding amic acids (9, 10), and their cyclisation to pyridazines (11) was examined; only the maleamic acid (10) was converted to the pyridazine (11).Maleic hydrazide (14) by condensation with p-acetamido-benzenesulfonyl chloride gave the O-sulfonyl pyridazine (15). 5-Chlorosalicylic acid-3-sulfonohydrazide (18) was prepared and characterized as the acetone and cyclohexanone hydrazones (19); but attempts to make aromatic hydrazones gave the azines (20). 5-Chlorosalicylic acid-3-sulfonyl azide (21) reacted with norbornene and triphenylphosphine to give the aziridine (22) and the phosphinimine (23).