625848-38-6

Basic information

• Product Name: 5-(4-[tert-butyl(dimethyl)silyloxy]phenyl)-3-[4'-(trifluoromethyl)phenyl]-2-pyrazinamine
• Synonyms: 5-(4-[tert-butyl(dimethyl)silyloxy]phenyl)-3-[4'-(trifluoromethyl)phenyl]-2-pyrazinamine
• CAS NO: 625848-38-6
• Molecular Weight: 445.56
• Mol File: 625848-38-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(4-[tert-butyl(dimethyl)silyloxy]phenyl)-3-[4'-(trifluoromethyl)phenyl]-2-pyrazinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-[tert-butyl(dimethyl)silyloxy]phenyl)-3-[4'-(trifluoromethyl)phenyl]-2-pyrazinamine(625848-38-6)
• EPA Substance Registry System: 5-(4-[tert-butyl(dimethyl)silyloxy]phenyl)-3-[4'-(trifluoromethyl)phenyl]-2-pyrazinamine(625848-38-6)

Safety Data

• Hazardous Substances Data: 625848-38-6(Hazardous Substances Data)

Upstream product

• 1178890-01-1 2-amino-3-bromo-5-[p-(t-butyldimethylsilyloxy)phenyl]-1,4-pyrazine 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 159191-56-7 (4-((tert-butyldimethylsilyl)oxy)phenyl)boronic acid 
• 625848-14-8 5-bromo-3-(4-(trifluoromethyl)phenyl)pyrazin-2-amine 

Downstream Products

• 1178890-04-4 2-amino-3-(4-trifluoromethylphenyl)-5-(4-hydroxyphenyl)-1,4-pyrazine 

Relevant articles and documents

In vitro and in vivo studies of 6,8-(diaryl)imidazo[1,2-a]pyrazin-3(7H)-ones as new antioxidants

A series of 5-aryl and 3,5-diaryl-2-amino-1,4-pyrazines and the derived imidazopyrazinones has been synthesized to study the chemical oxidative degradation of the bicyclic systems in vitro. Imidazopyrazinones mainly degraded following two independent pathways producing their precursors, namely aminopyrazines, and the corresponding amidopyrazines, respectively. Despite the fact that there is no influence of the substituent of the 3-aryl group on the ratio of the products aminopyrazine/amidopyrazine, diarylimidazopyrazinones and diarylaminopyrazines are good antioxidants in vivo. They protected against microvascular damages in ischemia/reperfusion with similar efficiencies.