6259-01-4Relevant articles and documents
Copper powder catalyzed direct ring-opening arylation of benzazoles with aryl iodides in polyethylene glycol
Yao, Lifang,Zhou, Qing,Han, Wei,Wei, Shaohua
supporting information, p. 6856 - 6860 (2013/02/22)
The expedient and efficient copper powder catalyzed direct ring-opening arylation of benzazoles with aryl iodides in polyethylene glycol that proceeds in the absence of an added ligand has been developed. The protocol provides facile access to 2-(arylthio)anilines and 2-phenoxyanilines in high yields with a wide tolerance of functional groups. Transmission electron microscopy confirmed that the active catalyst results from the in situ generation of copper nanoparticles under standard reaction conditions, which is an alternative avenue to develop a highly effective metallic copper catalyst. Moreover, the catalytic system can be recycled up to six times. Copyright
One-pot synthesis of amine-substituted aryl sulfides and benzo[ b ]thiophene derivatives
Duan, Zhongyu,Ranjit, Sadananda,Liu, Xiaogang
supporting information; experimental part, p. 2430 - 2433 (2010/07/10)
A series of amine-substituted aryl sulfides have been synthesized from nitroaryl halides via a simple one-pot procedure involving metal-free C-S cross-coupling and in situ nitro group reduction. Various nitroaryl halides were reacted with thiols in recyclable poly(ethylene glycol) to afford the amine-substituted aryl sulfides in high yield. Additionally, the cross-coupling reactions of nitro- and aldehyde-substituted aryl halides with benzyl thiols under the same reaction conditions were demonstrated to afford benzothiazole and phenylbenzo[b]thiophene derivatives.
