62718-34-7

Basic information

• Product Name: Cyclohexanecarbonitrile, 1-methyl-
• Synonyms: 1-methylcyclohexanecarbonitrile;1-Methylcyclohexacarbonitrile;1-Methyl-cyan-cyclohexan;1-methylcyclohexylcarbonitrile;Cyclohexanecarbonitrile,1-methyl;1-Methylcyclohexylnitril;1-Methyl-cyclohexancarbonitril;1-methyl-cyclohexane-1-carbonitrile;Cyclohexanecarbonitrile,methyl
• CAS NO: 62718-34-7
• Molecular Formula: C8H13N
• Molecular Weight: 123.198
• Mol File: 62718-34-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 181-182 °C
• Density: 0.90±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Cyclohexanecarbonitrile, 1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarbonitrile, 1-methyl-(62718-34-7)
• EPA Substance Registry System: Cyclohexanecarbonitrile, 1-methyl-(62718-34-7)

Safety Data

• Hazardous Substances Data: 62718-34-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 93, p. 4318, 1971 DOI: 10.1021/ja00746a052The Journal of Organic Chemistry, 46, p. 2985, 1981 DOI: 10.1021/jo00327a034

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 931-78-2 1-chloro-1-methylcyclohexane 
• 14064-13-2 (1-methylcyclohexyl)methanol 
• 108-94-1 cyclohexanone 
• 61827-29-0 1-(1-Cyanocyclohexyl)-2-carbomethoxyhydrazine 
• 86559-21-9 1-isocyano-1-methyl-cyclohexane 
• 590-67-0 1-Methylcyclohexanol 
• 143-33-9 sodium cyanide 
• 33670-04-1 Methyl N-(1-cyanocyclohexyl)-diazoformiat 
• 74-88-4 methyl iodide 
• 103168-39-4 1-Methyl-1-diaminomethyl-N.N'-bis-<1-methyl-cyclohexylmethylen>-cyclohexan 

Downstream Products

• 1123-25-7 1-methyl-1-cyclohexanecarboxylic acid 

Relevant articles and documents

Simple one-pot conversion of alcohols into nitriles

Various benzylic and primary alcohols were efficiently converted into the corresponding nitriles in good yields at room temperature by treatment with tert-butyl hypochlorite, diiodine, or 1,3-diiodo-5,5-dimethylhydantoin in the presence of (2,2,6,6-tetramethylpiperidin-1-yl)oxidanyl (TEMPO), followed by treatment with diiodine and aqueous ammonia. The nitriles were obtained in good yields and high purities simply by extraction of the reaction mixture with chloroform and subsequent removal of the solvent.

TRIMETHYLSILYL CYANIDE PROMOTED CYANATION OF TERTIARY ALKYL CHLORIDES AND OTHER SN1 ACTIVE COMPOUNDS

Tertiary chlorides are readily cyanated in a one-pot procedure using trimethylsilyl cyanide in the presence of SnCl4.The mechanism of this novel and synthetically useful reaction involves initial isonitrile formation followed by rearrangement to the tertiary nitrile.Other SN1 active compounds also undergo smooth cyanation.

Cyanierung tertiaerer Alkylchloride: Eine neue Methode zur geminalen Dialkylierung von Ketonen

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