6279-47-6

Basic information

• Product Name: ETHYL 2,6-DIMETHYLPHENOXYACETATE
• Synonyms: ETHYL 2,6-DIMETHYLPHENOXYACETATE;(2,6-Xylyloxy)acetic Acid Ethyl Ester;2-(2,6-DiMethylphenoxy)acetic Acid Ethyl Ester;NSC 11352
• CAS NO: 6279-47-6
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.25364
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 6279-47-6.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 279.6 °C at 760 mmHg
• Flash Point: 112.3 °C
• Appearance: slightly-yellowish oil
• Density: 1.046 g/cm³
• Vapor Pressure: 0.00398mmHg at 25°C
• Refractive Index: 1.497
• Solubility: Chloroform, Dichloromethane
• CAS DataBase Reference: ETHYL 2,6-DIMETHYLPHENOXYACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2,6-DIMETHYLPHENOXYACETATE(6279-47-6)
• EPA Substance Registry System: ETHYL 2,6-DIMETHYLPHENOXYACETATE(6279-47-6)

Safety Data

• Hazardous Substances Data: 6279-47-6(Hazardous Substances Data)

Usage

Description

ETHYL 2,6-DIMETHYLPHENOXYACETATE, also known as Ethyl 2,6-Dimethylphenoxyacetate, is an organic compound with the CAS number 6279-47-6. It is characterized by its slightly-yellowish oil appearance and is primarily used in the field of organic synthesis.

Uses

Used in Organic Synthesis:
ETHYL 2,6-DIMETHYLPHENOXYACETATE is used as a synthetic intermediate for the production of various organic compounds. Its unique chemical structure allows it to be a versatile building block in the synthesis of different molecules, contributing to the development of new materials and chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, ETHYL 2,6-DIMETHYLPHENOXYACETATE is used as a key component in the development of new drugs. Its chemical properties make it suitable for the synthesis of various pharmaceutical compounds, potentially leading to the discovery of novel therapeutic agents.
Used in Chemical Research:
ETHYL 2,6-DIMETHYLPHENOXYACETATE is also utilized in chemical research as a model compound for studying various reaction mechanisms and exploring new synthetic routes. This helps researchers gain a deeper understanding of organic chemistry and develop innovative approaches to chemical synthesis.
Used in Flavor and Fragrance Industry:
Due to its unique chemical structure, ETHYL 2,6-DIMETHYLPHENOXYACETATE can be used as a component in the creation of new flavors and fragrances. It can contribute to the development of novel scents and tastes, enhancing the sensory experience of various products in the flavor and fragrance industry.

InChI:InChI=1/C12H16O3/c1-4-14-11(13)8-15-12-9(2)6-5-7-10(12)3/h5-7H,4,8H2,1-3H3

Upstream product

• 576-26-1 2.6-dimethylphenol 
• 105-39-5 chloroacetic acid ethyl ester 
• 64-17-5 ethanol 
• 16081-16-6 sodium 2,6-dimethylphenolate 
• 3926-62-3 sodium monochloroacetic acid 
• 105-36-2 ethyl bromoacetate 
• 623-73-4 diazoacetic acid ethyl ester 

Downstream Products

• 64106-78-1 2-(2,6-dimethylphenoxy)acetohydrazide 
• 114305-83-8 2,6-Dimethyl-phenoxyacethydroxamsaeure 
• 13335-71-2 2-(2,6-dimethylphenoxy)acetic acid 
• 16737-71-6 2-(2,6-dimethylphenoxy)ethanol 
• 1798014-18-2 (R)-N-{(1R,3R,4R)-1-Benzyl-4-[2-(2,6-dimethyl-phenoxy)-acetylamino]-3-hydroxy-5-phenyl-pentyl}-3-methyl-2-(2-oxo-tetrahydro-pyrimidin-1-yl)-butyramide 
• 264884-01-7 N-{(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-(4-nitro-benzenesulfonyl)-amino]-propyl}-2-(2,6-dimethyl-phenoxy)-acetamide 
• 154612-58-5 (2S,4R)-1-{(2R,3S)-3-[2-(2,6-Dimethyl-phenoxy)-acetylamino]-2-hydroxy-4-phenyl-butyl}-4-(pyridin-4-ylsulfanyl)-piperidine-2-carboxylic acid tert-butylamide 
• 64013-45-2 1-(2,6-dimethylphenoxyacetyl)-4-phenylthiosemicarbazide 
• 64013-47-4 1-(2,6-dimethylphenoxyacetyl)-4-(4-methylphenyl)thiosemicarbazide 
• 64013-46-3 1-(2,6-dimethylphenoxyacetyl)-4-(2-methylphenyl)thiosemicarbazide 
• 64013-52-1 1-(2,6-dimethylphenoxyacetyl)-4-(4-chlorophenyl)thiosemicarbazide 
• 64013-48-5 1-(2,6-dimethylphenoxyacetyl)-4-(2,4-dimethylphenyl)thiosemicarbazide 
• 64013-51-0 1-(2,6-dimethylphenoxyacetyl)-4-(4-methoxyphenyl)thiosemicarbazide 
• 64013-50-9 1-(2,6-dimethylphenoxyacetyl)-4-(2-methoxyphenyl)thiosemicarbazide 

Relevant articles and documents

Production process of 2, 6-dimethylphenoxyacetic acid

The invention discloses a production process of 2, 6-dimethylphenoxyacetic acid, and belongs to the technical field of organic chemical industry. The upstream product 2, 6-dimethyl phenoxy acetic acidof 2, 6-dimethyl phenoxy acetyl chloride is prepared by controlling the two steps of substitution reaction and ester hydrolysis reaction, and the prepared 2, 6-dimethyl phenoxy acetic acid is high inpurity, does not generate large impurities, and is beneficial to subsequent preparation of lopinavir.

Carbene Transfer and Carbene Insertion Reactions Catalyzed by a Mixed-Ligand Copper(I) Complex

The catalytic activity of the mixed-ligand copper(I) complex [Cu(PPh3)2(κ2-O,O"-lact)] (1) {lact = l-(+)-lactate} has been investigated in carbene transfer and carbene insertion reactions. Complex 1 catalytically promoted the diastereoselective cyclopropanation of olefins in the presence of ethyl diazoacetate (EDA), under mild conditions, and with a low catalyst loading (1 mol-%). In the case of internal alkenes, a trans/cis ratio of up to 93:7 was reached. Moreover, compound 1 easily promoted the insertion of the carbene fragment deriving from the decomposition of ethyl diazoacetate into O–H (alcohols and phenols) and N–H (amine) bonds, with formation of the corresponding ethyl 2-alkoxyacetate, ethyl 2-phenoxyacetate, and ethyl 2-aminoacetate derivatives in good to high yields.

Synthesis and Herbicidal Activity of Some Novel Pyrazole Derivatives

Some novel pyrazole derivatives were designed and synthesized through multi-step reactions from substituted phenol as starting material. Their structures were confirmed by 1H NMR, FTIR, MS and elemental analysis. All these compounds were evaluated their herbicidal activity. The preliminary bioassay results indicated that some of title compounds displayed moderate herbicidal activity at 200 μg/mL. Among them, compounds 4-chloro-N'-(2-(2,5-dimethyl-phenoxy) acetyl)-3-ethyl-1-methyl-1H-pyrazole-5-carbohydrazide, 4-chloro-N'-(2-(2,4-dichlorophenoxy)acetyl)- 3-ethyl-1-methyl-1H-pyrazole-5-carbohydrazide, 4-chloro-3-ethyl-1-methyl-N'-(2-(m-tolyloxy) acetyl)-1H-pyrazole-5-carbohydrazide and 4-chloro-3-ethyl-1-methyl-N'-(2-(3-nitrophenoxy)acetyl)- 1H-pyrazole-5-car-bohydrazide possessed 95%, 100%, 95% and 95% inhibition against Brassica campestris respectively. In the further bioassay, the compound 6l exhibited excellent herbicidal activity either monocotyledon or dicotyledon plant at 150 g/ha.