627908-92-3

Basic information

• Product Name: SU14813
• Synonyms: SU14813;5-[(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
• CAS NO: 627908-92-3
• Molecular Formula: C23H27FN4O4
• Molecular Weight: 442.4832832
• Mol File: 627908-92-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 685.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.341
• PKA: 11.24±0.20(Predicted)
• CAS DataBase Reference: SU14813(CAS DataBase Reference)
• NIST Chemistry Reference: SU14813(627908-92-3)
• EPA Substance Registry System: SU14813(627908-92-3)

Safety Data

• Hazardous Substances Data: 627908-92-3(Hazardous Substances Data)

Usage

General Description

SU14813 is a chemical compound that belongs to the class of pyrazolyl-thiazoles and is potentially useful in cancer treatment. It is an inhibitor of multiple tyrosine kinases, including VEGFR-2, PDGFR-β, and KIT, with potential anti-angiogenic and anti-cancer activities. By inhibiting the activity of these kinases, SU14813 disrupts signaling pathways involved in tumor angiogenesis and growth, potentially leading to tumor regression and inhibition of metastasis. SU14813 has been studied in preclinical and early clinical trials for its potential in cancer therapy and has shown promise in inhibiting the proliferation of cancer cells in various cancer types. Further research and development of SU14813 may lead to its potential use as a targeted therapy for cancer treatment.