6288-89-7

Basic information

• Product Name: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine
• Synonyms: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine
• CAS NO: 6288-89-7
• Molecular Formula: C₇H₈N₄S₂
• Molecular Weight: 212.29522
• Mol File: 6288-89-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 482.6°C at 760 mmHg
• Flash Point: 245.6°C
• Appearance: /
• Density: 1.48g/cm³
• Vapor Pressure: 5.3E-09mmHg at 25°C
• Refractive Index: 1.727
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(6288-89-7)
• EPA Substance Registry System: 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine(6288-89-7)

Safety Data

• Hazardous Substances Data: 6288-89-7(Hazardous Substances Data)

Usage

General Description

4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine is a heterocyclic compound with potential pharmacological properties. It is a member of the pyrazolo[3,4-d]pyrimidine family and contains two methylthio groups attached to the 4th and 6th positions of the pyrazolo[3,4-d]pyrimidine ring. 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine has been studied for its potential use in medicinal chemistry, particularly in the development of novel pharmaceuticals with antiproliferative and antitumor activities. It has also been investigated for its potential as an antiviral agent against certain strains of viruses. Additionally, 4,6-Bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine has shown potential as an anti-inflammatory and antioxidant agent in preclinical studies. Due to its diverse pharmacological properties, this compound continues to be of interest for further research and development in the field of medicinal chemistry.

InChI:InChI=1/C7H8N4S2/c1-12-6-4-3-8-11-5(4)9-7(10-6)13-2/h3H,1-2H3,(H,8,9,10,11)

Upstream product

• 6288-85-3 6-chloro-4-methylsulfanyl-1⁽²⁾H-pyrazolo[3,4-d]pyrimidine 
• 74-93-1 methylthiol 
• 5334-32-7 1⁽²⁾,7-dihydro-pyrazolo[3,4-d]pyrimidine-4,6-dithione 
• 74-88-4 methyl iodide 
• 42754-96-1 4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine 
• 5334-32-7 1H-pyrazolo[3,4-d]pyrimidin-4,6-dithione 
• 2465-59-0 oxypurinol 
• 5334-33-8 4,5-Dihydro-4-thioxo-1H-pyrazolo[3,4-d]pyrimidin-6(7H)-one 
• 7508-59-0 6-chloro-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-thione 
• 100047-41-4 4-methylsulfanyl-1,7-dihydro-pyrazolo[3,4-d]pyrimidin-6-one 

Downstream Products

• 115523-39-2 1-(2'-benzoyloxyethoxymethyl)-4,6-dimethylthiopyrazolo<3,4-d>pyrimidine 
• 124684-78-2 4,6-Dimethylthio-1-β-(2,3,5-tri-O-benzyl-D-arabinofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 126867-61-6 4,6-Bis(methylthio)-2-propyl-2H-pyrazolo<3,4-d>pyrimidine 
• 126867-54-7 4,6-Bis(methylthio)-1-propyl-1H-pyrazolo<3,4-d>pyrimidine 
• 126867-64-9 2-Benzyl-4,6-bis-methylsulfanyl-2H-pyrazolo[3,4-d]pyrimidine 
• 126867-57-0 1-Benzyl-4,6-bis-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidine 
• 124469-66-5 2-(3'-cyclohexenyl)-4,6-dimethylthio-2H-pyrazolo<3,4-d>pyrimidine 
• 124469-65-4 1-(3'-cyclohexenyl)-4,6-dimethylthio-1H-pyrazolo<3,4-d>pyrimidine 
• 116019-22-8 4,6-dimethylthio-1-(2',3',5'-tri-O-benzoyl-α-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 116019-21-7 4,6-dimethylthio-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)pyrazolo<3,4-d>pyrimidine 
• 70011-76-6 1-methyl-4,6-dimethylthiopyrazolo[3,4-d]pyrimidine 
• 126867-52-5 2-Methyl-4,6-bis-methylsulfanyl-2H-pyrazolo[3,4-d]pyrimidine 
• 938062-94-3 1-(3-acetoxy-2-benzoyloxy-1-propoxy)methyl-3-bromo-4,6-dimethylthio-1H-pyrazolo[3,4-d]pyrimidine 
• 153901-75-8 4-amino-2-(2',2'-diethoxyethyl)-6-methylthio-2H-pyrazolo<3,4-d>pyrimidine 

Relevant articles and documents

Synthesis and antiviral activity of some C2-, C4-, and C6-substituted pyrazolo[3,4-d]pyrimidine acyclonucleosides with the alkylating chains of ACV, HBG, and iso-DHPG

A useful route to obtain trisubstituted pyrazolo[3,4-d]pyrimidines 14-17 is described. Those later were coupled with the alkylating agents 18-20 as in ACV, HBG, and iso-DHPG to give, after deprotection, the desired acylonucleosides 33-44 . Almost all of t