62984-48-9

Basic information

• Product Name: N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide
• CAS NO: 62984-48-9
• Molecular Formula: C₁₃H₁₀BrN₃O
• Molecular Weight: 304.146
• Mol File: 62984-48-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.45g/cm³
• CAS DataBase Reference: N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide(62984-48-9)
• EPA Substance Registry System: N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide(62984-48-9)

Safety Data

• Hazardous Substances Data: 62984-48-9(Hazardous Substances Data)

Usage

Description

N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide is a chemical compound with the molecular formula C14H10BrN3O. It is a derivative of pyridine-4-carboxamide and contains a bromophenyl group attached to the nitrogen atom. N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide is of interest in various scientific fields due to its specific properties, reactivity, and potential uses.

Uses

Used in Chemical Research:
N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide is used as a research chemical for studying its properties and reactivity. Its unique structure allows scientists to explore its behavior in various chemical reactions and interactions.
Used in Pharmaceutical and Medicinal Chemistry:
In the pharmaceutical and medicinal chemistry industry, N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide is used as a potential candidate for the development of new drugs. Its specific structural features may contribute to the creation of novel therapeutic agents.
Used in the Development of New Materials:
N-[(4-bromophenyl)methylideneamino]pyridine-4-carboxamide may also be used as a precursor to other organic compounds or in the development of new materials. Its unique chemical properties could be harnessed to create innovative materials with specific applications in various industries.

Upstream product

• 54-85-3 isoniazid 
• 1122-91-4 4-bromo-benzaldehyde 
• 55-22-1 pyridine-4-carboxylic acid 

Downstream Products

• 1430799-98-6 1-(2-(4-bromophenyl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-3(2H)-yl)ethanone 

Relevant articles and documents

(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors

Fourteen (hetero-)(arylidene)arylhydrazide derivatives (ABH1-ABH14) were synthesized, and their inhibitory activities against monoamine oxidases (MAOs) and acetylcholinesterase (AChE) were evaluated. Compound ABH5 most potently inhibited MAO-B with an IC5

New isoniazid derivatives with improved pharmaco-toxicological profile: Obtaining, characterization and biological evaluation

Tuberculostatic drugs are the most common drug groups with global hepatotoxicity. Awareness of potentially severe hepatotoxic reactions is vital, as hepatic impairment can be a devastating and often fatal condition. The treatment problems that may arise, within this class of medicines, are mainly of two types: adverse reactions (collateral, toxic or hypersensitive reactions) and the initial or acquired resistance of Mycobacterium tuberculosis to one or more antituberculosis drugs. Prevention of adverse reactions, increase treatment adherence and success rates, providing better control of tuberculosis (TB). In this regard, obtaining new drugs with low toxicity and high tuberculostatic potential is essential. Thus, in this work, we have designed or synthesized new derivatives of isoniazid (INH), such as new Isonicotinoylhydrazone (INH-a, INH-b and INH-c). These derivatives demonstrated good biocompatibility, antimicrobial property similar to that of parent isoniazid and last but not least, a significantly improved Pharmacotoxicological profile compared to that of isoniazid.

Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto-5′-nucleotidase

A series of isonicotinohydrazide derivatives was synthesized and tested against recombinant human and rat ecto-5′-nucleotidases (h-e5′NT and r-e5′NT) and alkaline phosphatase isozymes including both bovine tissue-non-specific alkaline phosphatase (b-TNAP)