63050-11-3Relevant articles and documents
A cocktail of165Er(iii) and Gd(iii) complexes for quantitative detection of zinc using SPECT and MRI
Malikidogo, Kyangwi P.,Da Silva, Isidro,Morfin, Jean-Fran?ois,Lacerda, Sara,Barantin, Laurent,Sauvage, Thierry,Sobilo, Julien,Lerondel, Stéphanie,Tóth, éva,Bonnet, Célia S.
supporting information, p. 7597 - 7600 (2018/07/15)
We propose quantitative assessment of zinc by combining nuclear and MR imaging. We use a cocktail of a Gd3+-complex providing a Zn2+-dependent MRI response and its165Er3+ analogue allowing for concentration assessment.165Er is readily obtained in a cyclotron and purified, which is indispensable for successful quantification of metal ions.
HETEROCYCLIC COMPOUND AND H1 RECEPTOR ANTAGONIST
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Paragraph 0184; 0185; 0186, (2013/04/13)
A heterocyclic compound useful as an antiallergic agent is provided. A compound represented by the following formula (1) or a salt thereof: wherein the ring A is a homocyclic or heterocyclic ring; the ring B is a heterocyclic ring which contains G and nitrogen atom N as constituent atoms thereof, wherein G is CH or N; R1 is a carbonyl group or an alkylene group; R2a and R2b are an alkyl group, a cycloalkyl group, an aryl group, or a heterocyclic group; X is an oxygen atom or a sulfur atom; Z is a hydroxyl group, an alkoxy group, a cycloalkyloxy group, an aryloxy group, an aralkyloxy group, an amino group, or an N-substituted amino group; and n is 0 or 1; with the proviso that when the ring A is a benzene ring or when the ring B is a piperazine ring, R1 is an alkylene group which may have a substituent.
BENZAZEPINE DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS
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Page/Page column 28-29, (2011/08/03)
A compound having the formula (1) wherein: Ra represents C1-6 alkyl, cyclobutyl or cyclopentyl; R1 represents H or C1-6 alkyl; R2 represents H or R1 and R2 together represent =0; X1 represents CR3 or N; X2 represents CR4 or N; X3 represents CR5 or N; X4 represents CR6 or N; wherein one or two of X1, X2, X3 and X4 represents N; R3, R4, R5 and R6 each independently represent H, C1-6 alkoxy or -NR7R8; R7 and R8 independently represent H or C1-6 alkyl; or R7 and R8 and the N atom to which they are attached are joined to form a N-containing heterocyclyl ring optionally substituted with one or more substituents independently selected from halogen, C1-6 alkyl and C1-6 alkoxy; or a pharmaceutically acceptable salt thereof, is provided. Compounds of the invention have been found to modulate the histamine H3 receptor.