63059-25-6

Basic information

• Product Name: 2-IODOBENZENESULFONIC ACID
• Synonyms: 2-IODOBENZENESULFONIC ACID;2-Iodobenzenesulphonic acid;2-iodobenzene-1-sulfonic acid;Benzenesulfonic acid, 2-iodo-;2-Iodobenzenesulfonic Acid Hydrate
• CAS NO: 63059-25-6
• Molecular Formula: C₆H₅IO₃S
• Molecular Weight: 284.07
• Product Categories: Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 63059-25-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 344-345 °C
• Appearance: /
• Density: 2.115 g/cm³
• Refractive Index: 1.667
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -1.01±0.15(Predicted)
• Water Solubility: Soluble in water
• CAS DataBase Reference: 2-IODOBENZENESULFONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODOBENZENESULFONIC ACID(63059-25-6)
• EPA Substance Registry System: 2-IODOBENZENESULFONIC ACID(63059-25-6)

Safety Data

• RIDADR: UN 3261 8/PG III
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 63059-25-6(Hazardous Substances Data)

Usage

General Description

2-Iodobenzenesulfonic Acid is a chemical compound with the formula C6H5IO3S. Belonging to the class of organic compounds known as benzenesulfonic acids, this compound gets characterized by a benzenesulfonic acid moiety. As a strong sulfonic acid consisting of benzenesulfonic acid having an iodo substituent at the 2-position, it is considered harmful by inhalation, ingestion, or skin absorption. It acts as a useful reagent in various chemical synthesis reactions. This chemical isn't found naturally and is exclusively synthesized for industrial applications in laboratories primarily. The reactivity of 2-Iodobenzenesulfonic Acid is known for its electrophilic substitution at the sulfonic acid group. It is also used as an intermediate in the production of other chemicals.

InChI:InChI=1/C6H5IO3S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H,8,9,10)

Upstream product

• 88-21-1 2-amino-1-benzenesulfonic acid 
• 1194059-82-9 2-[(4-methoxyphenyl)iodonio]benzenesulfonate 
• 98-80-6 phenylboronic acid 
• 63059-29-0 2-iodobenzene-1-sulfonyl chloride 

Downstream Products

• 64297-61-6 2-iodosobenzenesulfonic acid 
• 63059-29-0 2-iodobenzene-1-sulfonyl chloride 
• 53730-99-7 2-iodobenzene-sulfonamide 
• 502-56-7 nonanone-5 
• 22172-71-0 3-phenylbenzo<1.3.2>dithiazolium ylide 1.1-dioxide 
• 64939-46-4 2-(4-bromophenylsulfanyl)benzenesulfonamide 
• 1345020-90-7 3-(4-bromophenyl)-1,3,2-benzodithiazolium ylide 1,1-dioxide 
• 22172-72-1 2-(phenylsulfanyl)benzenesulfonamide 

Relevant articles and documents

Preparation and X-ray structure of 2-iodoxybenzenesulfonic acid (IBS) – A powerful hypervalent iodine(V) oxidant

The selective preparation of 2-iodoxybenzenesulfonic acid (IBS, as potassium or sodium salts) by oxidation of sodium 2-iodoben-zenesulfonate with Oxone or sodium periodate in water is reported. The single crystal X-ray diffraction analysis reveals a compl

Switchable Divergent Synthesis in Gold-Catalyzed Difunctionalizations of o-Alkynylbenzenesulfonamides with Aryldiazonium Salts

Gold-catalyzed difunctionalizations of o-alkynylbenzenesulfonamides with aryldiazonium salts are reported herein. Upon irradiation with the blue LEDs, benzosultam products were formed via aminoarylation accompanied by the release of N2. Without irradiatio

One-pot, Pd/Cu-catalysed synthesis of alkynyl-substituted 3-ylidene-dihydrobenzo[d]isothiazole 1,1-dioxides

Enyne-substituted benzoisothiazole derivatives have been synthesised under one-pot, operationally simple conditions using 2-iodo-N-(trimethylsilylethynyl)benzenesulfonamides and terminal alkynes as starting materials and a palladium–copper-based catalytic system. The structure of these heterocycles has been demonstrated by NMR spectroscopy and confirmed by X-ray crystallographic analysis. A plausible reaction mechanism has been proposed.