63082-45-1

Basic information

• Product Name: 4-Fluoro-2-methylbenzaldehyde
• Synonyms: 4-FLUORO-2-METHYLBENZALDEHYDE;Benzaldehyde, 4-fluoro-2-methyl- (9CI);2-methyl-4-fluorobenzaldehyde;4-Fluoro-o-tolualdehyde;5-Fluoro-2-formyltoluene;5-Fluoro-2-formyltoluene, 4-Fluoro-o-tolualdehyde;Benzaldehyde, 4-fluoro-2-methyl-;4-Fluoro-2-methylbenzaldehyde 97%
• CAS NO: 63082-45-1
• Molecular Formula: C₈H₇FO
• Molecular Weight: 138.14
• EINECS: 1312995-182-4
• Product Categories: ALDEHYDE;Fluorobenzene;Carbonyl Compounds;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;Aldehydes;C8;Carbonyl Compounds;Benzaldehyde series
• Mol File: 63082-45-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 87 14mm
• Flash Point: 82 °C
• Appearance: /
• Density: 1.144 g/mL at 25 °C
• Vapor Pressure: 0.235mmHg at 25°C
• Refractive Index: 1.5260
• Storage Temp.: Room temperature.
• Sensitive: Air Sensitive
• CAS DataBase Reference: 4-Fluoro-2-methylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluoro-2-methylbenzaldehyde(63082-45-1)
• EPA Substance Registry System: 4-Fluoro-2-methylbenzaldehyde(63082-45-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-41-37/38
• Safety Statements: 26-36-39
• WGK Germany: 3
• Hazardous Substances Data: 63082-45-1(Hazardous Substances Data)

Usage

Description

4-Fluoro-2-methylbenzaldehyde, also known as 4-Fluoro-o-tolualdehyde, is an organic compound belonging to the family of benzaldehyde derivatives. It is characterized by the presence of a fluorine atom at the para position and a methyl group at the ortho position relative to the aldehyde functional group. 4-Fluoro-2-methylbenzaldehyde exhibits a clear colorless to light yellow liquid appearance and is widely utilized in various research applications due to its unique chemical properties.

Uses

Used in Research and Development:
4-Fluoro-2-methylbenzaldehyde is used as a valuable research chemical for the synthesis of various complex organic molecules and pharmaceutical compounds. Its unique structure and reactivity make it a versatile building block in the development of novel drugs and advanced materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Fluoro-2-methylbenzaldehyde is employed as a key intermediate in the synthesis of various medicinal agents. Its distinct chemical properties allow for the creation of new drug candidates with potential therapeutic applications, contributing to the advancement of medical treatments.
Used in Flavor and Fragrance Industry:
4-Fluoro-2-methylbenzaldehyde is also utilized in the flavor and fragrance industry as a component in the creation of unique scents and flavors. Its distinct aromatic profile can be used to develop new fragrances or enhance existing ones, providing a wide range of possibilities for perfumers and flavorists.
Used in Material Science:
In the field of material science, 4-Fluoro-2-methylbenzaldehyde can be used as a precursor to develop novel materials with specific properties, such as improved stability, enhanced reactivity, or unique optical characteristics. Its incorporation into various materials can lead to the creation of innovative products with diverse applications.

Purification Methods

The aldehyde has been purified by gas chromatography and should be kept under N2 as it readily oxidizes in air [Burgess et al. Aust J Chem 30 543 1977].

InChI:InChI=1/C8H7FO/c1-6-4-8(9)3-2-7(6)5-10/h2-5H,1H3

Upstream product

• 452-71-1 4-fluor-2-methylaniline 
• 452-63-1 2-Bromo-5-fluorotoluene 
• 68-12-2 N,N-dimethyl-formamide 
• 95-52-3 2-Fluorotoluene 
• 201230-82-2 carbon monoxide 
• 202865-83-6 1-bromo-3-fluoro-5-methylbenzene 
• 80141-91-9 (4-fluoro-2-methylphenyl)methanol 

Downstream Products

• 137586-78-8 3-(4-Fluoro-2-methylphenyl)-1-phenyl-2-propen-1-one 
• 946123-51-9 C₂₁H₁₈NF 
• 943441-91-6 (S)-1-benzhydryl-2-(4-fluoro-2-methylphenyl)-2,3-dihydropyridin-4(1H)-one 
• 137586-81-3 4-(4-Fluoro-2-methylphenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinecarboxaldehyde 
• 137587-00-9 4-(4-Fluoro-2-methyl-phenyl)-3-((E)-2-iodo-vinyl)-2-isopropyl-6-phenyl-pyridine 
• 135426-34-5 4-(4-Fluoro-2-methylphenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinemethanol 
• 135426-57-2 3-(2,2-Dibromoethenyl)-4-(4-fluoro-2-methylphenyl)-2-(1-methylethyl)-6-phenylpyridine 
• 137586-80-2 4-(4-Fluoro-2-methylphenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinecarboxylic acid, ethyl ester 
• 137586-79-9 β-(4-Fluoro-2-methylphenyl)-α-(2-methyl-1-oxopropyl)-Δ-oxobenzenepentanoic acid, ethyl ester 
• 137587-01-0 (S)-4-({2-[4-(4-Fluoro-2-methyl-phenyl)-2-isopropyl-6-phenyl-pyridin-3-yl]-ethyl}-methoxy-phosphinoyl)-3-hydroxy-butyric acid methyl ester 
• 137586-83-5 (S)-4-{[4-(4-Fluoro-2-methyl-phenyl)-2-isopropyl-6-phenyl-pyridin-3-ylethynyl]-methoxy-phosphinoyl}-3-hydroxy-butyric acid methyl ester 
• 137593-79-4 (S)-4-({(E)-2-[4-(4-Fluoro-2-methyl-phenyl)-2-isopropyl-6-phenyl-pyridin-3-yl]-vinyl}-methoxy-phosphinoyl)-3-hydroxy-butyric acid methyl ester 
• 137593-78-3 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-4-({(E)-2-[4-(4-fluoro-2-methyl-phenyl)-2-isopropyl-6-phenyl-pyridin-3-yl]-vinyl}-methoxy-phosphinoyl)-butyric acid methyl ester 
• 137635-19-9 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-4-{[4-(4-fluoro-2-methyl-phenyl)-2-isopropyl-6-phenyl-pyridin-3-ylethynyl]-methoxy-phosphinoyl}-butyric acid methyl ester 

Relevant articles and documents

Efficient and Highly Selective Solvent-Free Oxidation of Primary Alcohols to Aldehydes Using Bucky Nanodiamond

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