6310-21-0

Basic information

• Product Name: 2-tert-Butylaniline
• Synonyms: 2-TERT-BUTYLANILINE;AKOS BBS-00003572;Aniline, 2-tert-butyl-;2-TERT-BUTYLPHENYLAMINE;2-(1,1-Dimethylethyl)benzenamine;2-tert-Butylbenzenamine;2-tert-Butylaniline,99%;2-tert-Butylaniline 98%
• CAS NO: 6310-21-0
• Molecular Formula: C₁₀H₁₅N
• Molecular Weight: 149.23
• EINECS: 228-634-5
• Product Categories: Aromatics;Anilines, Aromatic Amines and Nitro Compounds;Amines;C9 to C10;Nitrogen Compounds
• Mol File: 6310-21-0.mol
• Article Data: 15

Chemical Properties

• Melting Point: −60 °C(lit.)
• Boiling Point: 123-124 °C17 mm Hg(lit.)
• Flash Point: 216 °F
• Appearance: Clear pale yellow to red-brown/Liquid
• Density: 0.957 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0525mmHg at 25°C
• Refractive Index: n20/D 1.545(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 3.78±0.10(Predicted)
• CAS DataBase Reference: 2-tert-Butylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-Butylaniline(6310-21-0)
• EPA Substance Registry System: 2-tert-Butylaniline(6310-21-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-37/39-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 6310-21-0(Hazardous Substances Data)

Usage

Description

2-tert-Butylaniline is an organic compound with the chemical formula C10H15N. It is a derivative of aniline, where a tert-butyl group is attached to the 2-position of the phenyl ring. 2-tert-Butylaniline is known for its unique chemical properties and potential applications in various fields.

Uses

Used in Chemical Synthesis:
2-tert-Butylaniline is used as a key intermediate in the synthesis of various organic compounds. It serves as a building block for the preparation of complex molecules with specific properties and functions.
Used in the Preparation of 2,3-bis(2-tert-butyl-phenyl-imino)butane:
2-tert-Butylaniline is used as a starting material for the preparation of 2,3-bis(2-tert-butyl-phenyl-imino)butane, a compound with potential applications in materials science and chemical research.
Used in the Preparation of N,N′-bis-(2-tert-butylphenyl)naphthalene-1,4,5,8-tetracarboxylic diimides:
2-tert-Butylaniline is used in the synthesis of two rotamers, antiand syn-N,N′-bis-(2-tert-butylphenyl)naphthalene-1,4,5,8-tetracarboxylic diimides. These compounds have been investigated for their guest inclusion abilities, which can be relevant in supramolecular chemistry and the development of new materials with specific host-guest interactions.

InChI:InChI=1/C10H15N/c1-10(2,3)8-6-4-5-7-9(8)11/h4-7H,11H2,1-3H3

Upstream product

• 1886-57-3 1-tert-butyl-2-nitrobenzene 
• 62-53-3 aniline 
• 115-11-7 isobutene 
• 253185-03-4 tert-butylbenzene 
• 75-28-5 Isobutane 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 7647-01-0 hydrogenchloride 
• 6310-20-9 4-Amino-2-nitro-tert-butylbenzene hydrochloride 
• 71-43-2 benzene 
• 3282-56-2 4-tert-butylnitrobenzene 
• 31951-12-9 4-tert-butyl-3-nitro-phenylamine 
• 4160-54-7 1-tert-butyl-2,4-dinitrobenzene 
• 59719-78-7 4-tert-butyl-3-nitrobenzoic acid 

Downstream Products

• 99858-67-0 N-(2-(tert-butyl)phenyl)formamide 
• 62171-59-9 1-(tert-butyl)-2-iodobenzene 
• 1728-46-7 2-tert-butylcyclohexanone 
• 38510-79-1 rac-6-tert-butylcyclohex-2-enone 
• 109932-97-0 (2-tert-butyl-phenyl)-methylamine 
• 103392-84-3 2-tert-Butyl-5-nitro-phenylamine 
• 105401-87-4 (2-tert-butyl-phenylsulfanyl)-acetic acid 
• 7402-70-2 N-(2-tert-butylphenyl)acetamide 
• 59238-67-4 N-(2-(tert-butyl)phenyl)benzamide 
• 32767-57-0 N-(2-tert-butyl-phenyl)-N'-phenyl-thiourea 
• 60530-65-6 N,N′-bis(4-tert-butylphenyl)formamidine 
• 17900-75-3 chloro-acetic acid-(2-tert-butyl-anilide) 
• 22025-87-2 o-tert-butyl-N,N-dimethylaniline 
• 111089-32-8 3-hydroxy-[2]naphthoic acid-(2-tert-butyl-anilide) 

Relevant articles and documents

Minimization of Back-Electron Transfer Enables the Elusive sp3 C?H Functionalization of Secondary Anilines

Anilines are some of the most used class of substrates for application in photoinduced electron transfer. N,N-Dialkyl-derivatives enable radical generation α to the N-atom by oxidation followed by deprotonation. This approach is however elusive to monosubstituted anilines owing to fast back-electron transfer (BET). Here we demonstrate that BET can be minimised by using photoredox catalysis in the presence of an exogenous alkylamine. This approach synergistically aids aniline SET oxidation and then accelerates the following deprotonation. In this way, the generation of α-anilinoalkyl radicals is now possible and these species can be used in a general sense to achieve divergent sp3 C?H functionalization.

Synthesis method of 4,4-diamino 3,3-di-tert-butyl diphenylmethane

The invention aims at providing a synthesis method of 4,4-diamino 3,3-di-tert-butyl diphenylmethane. According to the process, o-tert-butyl aniline is used as raw materials to perform further a condensation reaction with formaldehyde under the effect of solid acid catalysts to obtain the 4,4-diamino 3,3-di-tert-butyl diphenylmethane. The reaction temperature is 90 to 150 DEG C; the reaction time is 1 to 8 hours. The o-tert-butyl aniline can be obtained through methyl tertiary butyl ether or tert-butyl alcohol alkylation reaction via aniline; the raw material cost is greatly reduced; the huge possibility is provided for the industrial application of the 4,4-diamino 3,3-di-tert-butyl diphenylmethane. The catalyst is montmorillonoid or kaolin with layered structures sold in the market. The catalyst can be cyclically used. High activity is realized on the synthesis of 4,4-diamino 3,3-di-tert-butyl diphenylmethane from the o-tert-butyl and the formaldehyde. The process belongs to a green environment-friendly and efficient synthesis process for the 4,4-diamino 3,3-di-tert-butyl diphenylmethane.

Rh2(II)-catalyzed intramolecular aliphatic C-H bond amination reactions using aryl azides as the N-atom source

Rhodium(II) dicarboxylate complexes were discovered to catalyze the intramolecular amination of unactivated primary, secondary, or tertiary aliphatic C-H bonds using aryl azides as the N-atom precursor. While a strong electron-withdrawing group on the nitrogen atom is typically required to achieve this reaction, we found that both electron-rich and electron-poor aryl azides are efficient sources for the metal nitrene reactive intermediate.