632325-56-5 Usage
General Description
5-Ethoxycarbonylthiophen-2-boronic acid is a chemical compound with the molecular formula C9H11BO4S and a molar mass of 222.05 g/mol. It is a boronic acid derivative with a thiophene ring and an ethoxycarbonyl group attached to the boron atom. 5-ETHOXYCARBONYLTHIOPHEN-2-BORONIC ACID is commonly used as a reagent in organic synthesis and medicinal chemistry, specifically in the development of pharmaceuticals and agrochemicals. Its boronic acid functionality allows it to participate in various organic reactions, making it a versatile building block for the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 632325-56-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,2,3,2 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 632325-56:
(8*6)+(7*3)+(6*2)+(5*3)+(4*2)+(3*5)+(2*5)+(1*6)=135
135 % 10 = 5
So 632325-56-5 is a valid CAS Registry Number.
632325-56-5Relevant articles and documents
Synthesis of 2,3-Substituted Thienylboronic Acids and Esters
Christophersen, Claus,Begtrup, Mikael,Ebdrup, Soren,Petersen, Henning,Vedso, Per
, p. 9513 - 9516 (2003)
A noncryogenic protocol for the synthesis of 2-substituted 3-thienylboronic acids and esters as well as 3-substituted 2-thienylboronic acids and esters has been developed. Electrophiles were introduced regiospecifically in the 2-position of 2,3-dibromothiophene and in the 3-position of 2-bromo-3-iodothiophene by halogen-magnesium exchange followed by quenching with electrophiles. Palladium-catalyzed borylation of the 2,3-substituted halothiophenes with pinacolborane and P(t-Bu)3 as ligand for Pd produced 9 and 10. The borylation protocol was tolerated by a range of functional groups; however, strongly electron-withdrawing substituents decreased the stability of the thienylboronic acids and esters.
