63399-13-3

Basic information

• Product Name: 1H-1,2,4-Triazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-
• CAS NO: 63399-13-3
• Molecular Formula: C17H13Cl4N3O
• Molecular Weight: 417.122
• Mol File: 63399-13-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-1,2,4-Triazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,4-Triazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-(63399-13-3)
• EPA Substance Registry System: 1H-1,2,4-Triazole, 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-(63399-13-3)

Safety Data

• Hazardous Substances Data: 63399-13-3(Hazardous Substances Data)

Upstream product

• 4252-78-2 2,2',4'-trichloroacetophenone 
• 95-50-1 1,2-dichloro-benzene 
• 94-99-5 2,4-Dichlorobenzyl chloride 
• 58905-16-1 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone 
• 58905-18-3 1-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-yl)-1-ethanol 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 
• 2631-72-3 2,4-dichlorophenacyl bromide 

Relevant articles and documents

Use of miconazole and derivatives thereof as TGR5 agonists (by machine translation)

The invention belongs to the technical field of medicines, and relates to novel application TGR5 of miconazole and derivatives thereof in treatment, of diseases and conditions of a biological pathologic process involved in treatment, and. The miconazole and the analogues thereof can activate TGR5 active, for use TGR5 in the treatment or prevention of diseases associated with, activity modulation. (by machine translation)

Aromatic ethers of 1-aryl 2-(1H-azolyl)ethanol: study of antifungal activity

Aromatic ethers related to antifungal azole miconazole were synthesized and tested against various strains of Candida.We found that activity is related to the nature of the aromatic ring and the position of substituents on this ring.Activity is more strongly dependent on the substituent in the 2-position of the ethyl chain on the aromatic group linked through the oxygen.Triazoles were always less potent than the corresponding imidazole analogues. - Keywords: imidazole; 1,2,4-triazole; antifungal activity; yeast; structure-activity relationship

1-Phenyl-2-(1,2,4-triazolyl-1-yl)-ethyl ether

1-Phenyl-2-(1,2,4-triazol-1-yl)-ethyl ethers of the formula STR1 in which R is halogen, alkyl, alkoxy, alkylthio, alkylsulfonyl, halogenoalkyl, nitro, cyano, optionally substituted phenyl or optionally substituted phenoxy, R' is alkyl, alkenyl, alkynyl, optionally substituted phenyl, optionally substituted benzyl or optionally substituted styryl, and n is 0, 1, 2 or 3, and their salts, which possess fungicidal and bactericidal properties.