6340-55-2 Usage
Description
2,6-DIMETHOXY-4-METHYLQUINOLINE, also known as 2-Chloro-6-methoxy-4-methylquinoline, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its quinoline structure, with a chlorine atom at the 2nd position, a methoxy group at the 6th position, and a methyl group at the 4th position. 2,6-DIMETHOXY-4-METHYLQUINOLINE plays a significant role in the development of new drugs with improved therapeutic properties and safety profiles.
Uses
Used in Pharmaceutical Industry:
2,6-DIMETHOXY-4-METHYLQUINOLINE is used as an intermediate in the synthesis of Tafenoquine-d3 Succinate, which is the labelled analog of Tafenoquine (T004760). Tafenoquine is a new 8-aminoquinoline with an enhanced therapeutic index and safety profile compared to primaquine (P733500). It has the potential to become a widely used drug in the prevention and treatment of malaria infections, particularly as resistant strains of Plasmodium species continue to emerge. The development of Tafenoquine and its analogs can lead to more effective and safer treatments for malaria, reducing the global burden of this disease.
Check Digit Verification of cas no
The CAS Registry Mumber 6340-55-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,4 and 0 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6340-55:
(6*6)+(5*3)+(4*4)+(3*0)+(2*5)+(1*5)=82
82 % 10 = 2
So 6340-55-2 is a valid CAS Registry Number.
InChI:InChI=1/C24H24N2O6/c1-4-7-16-12-15(14-20(21(16)27)32-6-3)13-19-22(28)25-24(30)26(23(19)29)17-8-10-18(11-9-17)31-5-2/h4,8-14,27H,1,5-7H2,2-3H3,(H,25,28,30)/b19-13+
6340-55-2Relevant articles and documents
Compounds having anticonvulsion activity, preparing methods thereof and applications of the compounds
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Paragraph 0061; 0062; 0063; 0064, (2017/10/05)
The invention provides 7-substituted-5-methyl-1,2,4-triazolo[4,3-a] quinoline and 7-substituted-5-ethoxy-[1,2,4]-triazolo[4,3-a] quinoline compounds having anticonvulsion activity, preparing methods thereof and applications of the compounds in the field of preparing anticonvulsion medicines.
Quinoline-4-acetamides as sPLA2 inhibitors
Liu, Ying,Feng, Yabing,Wang, Renxiao,Gao, Ying,Lai, Luhua
, p. 1639 - 1641 (2007/10/03)
Quinoline-4-acetamides were designed as potential phospholipase A2 inhibitors by structural based method and synthesized. The chemical structures of the obtained compounds were confirmed by elemental analyses, 1H NMR and MS. Preliminary bioassay study shows that quinoline-4-acetamides display certain inhibition to sPLA2.
Substituted thiosemicarbazido/semicarbazido quinolines as possible antimalarials
Mehrotra,Barthwal,Pandey,et al.
, p. 1213 - 1214 (2007/10/02)
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