6344-95-2

Basic information

• Product Name: 2,3-dibromo-1-(5-chloro-2-hydroxyphenyl)-3-phenylpropan-1-one
• CAS NO: 6344-95-2
• Molecular Formula: C₁₅H₁₁Br₂ClO₂
• Molecular Weight: 418.5076
• Mol File: 6344-95-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 474.3°C at 760 mmHg
• Flash Point: 240.6°C
• Density: 1.773g/cm³
• Vapor Pressure: 1.28E-09mmHg at 25°C
• Refractive Index: 1.664
• CAS DataBase Reference: 2,3-dibromo-1-(5-chloro-2-hydroxyphenyl)-3-phenylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dibromo-1-(5-chloro-2-hydroxyphenyl)-3-phenylpropan-1-one(6344-95-2)
• EPA Substance Registry System: 2,3-dibromo-1-(5-chloro-2-hydroxyphenyl)-3-phenylpropan-1-one(6344-95-2)

Safety Data

• Hazardous Substances Data: 6344-95-2(Hazardous Substances Data)

Usage

General Description

The chemical "2,3-dibromo-1-(5-chloro-2-hydroxyphenyl)-3-phenylpropan-1-one" is a compound with the molecular formula C15H11Br2ClO2. It is a yellow solid that is commonly used as a building block in organic synthesis. 2,3-dibromo-1-(5-chloro-2-hydroxyphenyl)-3-phenylpropan-1-one contains two bromine atoms, a chlorine atom, a hydroxyphenyl group, and a phenylpropanone moiety. It is often used in the pharmaceutical industry as an intermediate in the synthesis of various drugs and pharmaceutical compounds. Additionally, it can also be used as a reagent in chemical reactions to introduce specific functional groups into organic molecules.

Upstream product

• 100-52-7 benzaldehyde 
• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 1218-24-2 3-phenyl-1-(2'-hydroxy-5'-chlorophenyl)-2-propen-1-one 

Downstream Products

• 3261-08-3 (Z)-2-benzylidene-5-chlorobenzofuran-3(2H)-one 
• 1363408-68-7 C₂₁H₁₅ClN₂O 

Relevant articles and documents

Synthesis and biological activities of some new quinoxalines

The condensation of 5-chloro-2-hydroxyacetophenone 1 with different substituted aromatic aldehydes in ethanol in presence of strong alkali furnished 1-(2-hydroxy-5-chlorophenyl)-3-aryl propen-1-ones 2a-e. Bromination of compounds 2a-e in acetic acid gave 1-(2-hydroxy-5-chlorophenyl)-3-aryl 2,3-dibromopropan-1-ones 3a-e which upon treatment with o-phenylenediamine in methanol in presence of cone sulphuric acid underwent cyclization and resulted in the formation of quinoxaline derivatives 4ae. Structures of compounds were established on the basis of analytical and spectral studies. Further these compounds were evaluated for their antimicrobial activities and some selected compounds were evaluated for antitubercular activities.