63469-49-8 Usage
Description
1-IODO-5-METHOXYNAPHTHALENE, with the molecular formula C11H9IO, is an iodinated derivative of 5-methoxynaphthalene. It is a chemical compound known for its high reactivity due to the presence of the iodine atom, making it a versatile building block for the synthesis of various organic molecules. 1-IODO-5-METHOXYNAPHTHALENE is a valuable asset in the field of organic chemistry, particularly in research and industrial applications.
Uses
Used in Pharmaceutical Development:
1-IODO-5-METHOXYNAPHTHALENE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to facilitate the creation of new medicinal compounds with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 1-IODO-5-METHOXYNAPHTHALENE is utilized as a starting material for the development of new agrochemicals, contributing to the advancement of crop protection and management solutions.
Used in Materials Science:
1-IODO-5-METHOXYNAPHTHALENE is employed as a component in the research and development of novel materials, leveraging its unique properties to enhance material characteristics in various applications.
Used as a Building Block in Organic Synthesis:
Across various chemical industries, 1-IODO-5-METHOXYNAPHTHALENE is used as a versatile building block for the synthesis of more complex organic compounds, enabling the creation of a wide array of chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 63469-49-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,4,6 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63469-49:
(7*6)+(6*3)+(5*4)+(4*6)+(3*9)+(2*4)+(1*9)=148
148 % 10 = 8
So 63469-49-8 is a valid CAS Registry Number.
63469-49-8Relevant articles and documents
Regioselective haloaromatization of 1,2-bis(ethynyl)benzene via halogen acids and PtCl2. Platinum-catalyzed 6-π electrocyclization of 1,2-bis(1′-haloethenyl)benzene intermediates
Lo, Ching-Yu,Kumar, Manyam Praveen,Chang, Hsu-Kai,Lush, Shie-Fu,Liu, Rai-Shung
, p. 10482 - 10487 (2007/10/03)
Treatment of 1,2-bis(ethynyl)benzene (1) with aqueous HX (X = Br, I) in hot 3-pentanone (100-105 °C, 2 h) afforded 1,2-bis(1′-haloethenyl)benzene species 2-Br and 2-I in 98% and 95% yields, respectively. The hydrochlorination of endiyne 1 failed to proceed at elevated temperature but was implemented efficiently by PtCl2 (5 mol %) in hot 3-pentanone (100 °C, 2 h) to give 1,2-bis(1′-chloroetheny)benzene 2-Cl in 80% yield. In the presence of PtCl2 (5 mol %), these halides 2-Cl, 2-Br, and 2-I were subsequently converted to 1-halonaphthalenes 3-Cl, 3-Br, and 3-I in the mother solution via sequential 6-π electrocyclization and dehalogenation reactions. PtCl2 (5 mol %) also effected direct haloaromatization of endiyne 1 with HX (X = Cl, Br, I) and gave 1-halonaphthalenes 3-Cl, 3-Br, and 3-I in 64-71% yields. This investigation reports the scope and the regioselectivity of haloaromatization of various enediynes catalyzed by PtCl2.
