63473-85-8

Basic information

• Product Name: Benzenepropanoic acid, b-butyl-, ethyl ester
• CAS NO: 63473-85-8
• Molecular Formula: C15H22O2
• Molecular Weight: 234.338
• Mol File: 63473-85-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, b-butyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, b-butyl-, ethyl ester(63473-85-8)
• EPA Substance Registry System: Benzenepropanoic acid, b-butyl-, ethyl ester(63473-85-8)

Safety Data

• Hazardous Substances Data: 63473-85-8(Hazardous Substances Data)

Upstream product

• 693-04-9 butyl magnesium bromide 
• 4192-77-2 ethyl cinnamate 
• 88626-90-8 BuMnCl 
• 1009-14-9 phenyl butyl ketone 
• 64-17-5 ethanol 
• 5638-30-2 acide 3-phenyl-heptanoique 
• 693-03-8 n-butyl magnesium bromide 
• 140-10-3 (E)-3-phenylacrylic acid 

Downstream Products

• 220629-78-7 3-Phenylheptanoyl chloride 
• 5638-30-2 acide 3-phenyl-heptanoique 
• 114376-30-6 3-Phenyl-1-heptanol 

Relevant articles and documents

ORGANOMANGANESE(II) REAGENTS XXII. COPPER-CATALYZED CONJUGATE ADDITION OF ORGANOMANGANESE REAGENTS TO α,β-ETHYLENIC ESTERS.

Copper-catalyzed conjugate addition of organomanganese reagents to α,β-ethylenic esters easily takes place in THF at 0 deg C, in the presence of 3 percent CuCl and Me3SiCl.Good to moderate yields are obtained from organomanganese reagents prepared from organolithium or organomagnesium compounds.

Efficient kinetic resolution in the asymmetric hydrosilylation of imines of 3-substituted indanones and 4-substituted tetralones

Kinetic resolution of the N-methyl imines of 3-substituted indanones and 4-substituted tetralones could be accomplished by hydrosilylation with a chiral titanocene catalyst. N-Methyl imines of 4-substituted tetralones were resolved to yield, after hydrolysis of the unreacted starting materials, ketones with high ee's and the amine products with high diastereomeric and enantiomeric purity. The utility of this process was demonstrated in the synthesis of sertraline.