636-12-4

Basic information

• Product Name: 4-Pyridinecarboxylic acid, 2-[[(4-fluorophenyl)amino]thioxomethyl]hydrazide
• CAS NO: 636-12-4
• Molecular Formula: C13H11FN4OS
• Molecular Weight: 290.321
• Mol File: 636-12-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 4-Pyridinecarboxylic acid, 2-[[(4-fluorophenyl)amino]thioxomethyl]hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinecarboxylic acid, 2-[[(4-fluorophenyl)amino]thioxomethyl]hydrazide(636-12-4)
• EPA Substance Registry System: 4-Pyridinecarboxylic acid, 2-[[(4-fluorophenyl)amino]thioxomethyl]hydrazide(636-12-4)

Safety Data

• Hazardous Substances Data: 636-12-4(Hazardous Substances Data)

Upstream product

• 54-85-3 isoniazid 
• 1544-68-9 4-fluorophenyl isothiocyanate 
• 19182-34-4 ammonium p-fluorophenyldithiocarbamate 
• 371-40-4 4-fluoroaniline 

Downstream Products

• 199111-94-9 4-(4-fluorophenyl)-5-(4-pyridinyl)-2,4-dihydro-3H-1,2,4-triazol-3-thione 
• 1392007-17-8 N-(4-fluorophenyl)-5-(pyridin-4-yl)-1,3,4-oxadiazol-2-amine 
• 199111-94-9 4-(4'-fluorophenyl)-5-(pyridin-4'-yl)-4H-1,2,4-triazole-3-thiol 

Relevant articles and documents

Design, synthesis and molluscicidal activity of new phosphorus compounds bearing fluorine substituted 1,2,4-triazolo[3,2-c][1,2,4]triazine derivatives

Novel phosphorus compounds bearing fluorine substituted 1,2,4-triazolo[3,2-c][1,2,4]triazine derivatives have been synthesized, starting from ring closure reactions of 3-hydrazino-4-(4`-fluorophenyl)-5-(prydin-4`-yl)-1,2,4-trizole (4) with 1,2-bioxygen co

Synthesis and antimicrobial activity of some new 1,2,4-trizoles

A series of 1,2,4-triazole derivatives were synthesized using appropriate synthetic route and structures were confirmed by IR,1H NMR and elemental analysis. All the synthesized compounds (6a-6h and 7a-7h) were evaluated for antimicrobial activity by determining their minimum inhibitory concentrations (MICs) against a panel of Gram-positive, Gram-negative bacteria and fungi. Most of the compounds showed significant antimicrobial activity against Gram-positive bacteria viz. S. aureus, B. subtilis, Gram-negative bacteria viz. E. coli, P. aerugenosa and fungi viz. C. albicans, A. niger. Some of the compounds showed better antibacterial activities against Gram-positive bacteria compared to Gram-negative bacteria. Compounds 7g, 6g, 6a exhibited good MICs against Gram-positive bacteria and 7f showed better MICs against Gram-negative bacteria compared to reference norfloxacin. Compounds 7f and 7d exhibited MICs which is equipotent to the reference drug ketoconazole.

Synthesis, structure and alkylation of 4-(4-Fluoro phenyl)-5-(isomeric pyridyl)-1,2,4-triazole-3-thiole

New 3,5-disubstituted-1,2,4-triazole and their derivatives 3(a-c) were synthesized in excellent yield by the intra molecular cyclization of 1,4- disubstituted thiosemicarbazides 2(a-c) with sodium hydroxide. Their further alkylation with methyl iodide in