63699-78-5

Basic information

• Product Name: L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT
• Synonyms: H-GLA(PNA)-OH;H-GLA(PNA)-OH NH3;H-GLU(3-CARBOXY-PNA)-OH;H-GLU(3-CARBOXY-PNA)-OH NH3;L-GLUTAMIC ACID-GAMMA-(3-CARBOXY-4-NITROANILIDE);L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT;L-GAMMA-GLUTAMYL-3-CARBOXY-4-NITROANILIDE AMMONIUM SALT;GLUTAMIC ACID 5-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT
• CAS NO: 63699-78-5
• Molecular Formula: C12H16N4O7
• Molecular Weight: 328.28
• EINECS: 264-418-7
• Mol File: 63699-78-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 718.3 °C at 760 mmHg
• Flash Point: 388.2 °C
• Appearance: /
• Vapor Pressure: 9.54E-20mmHg at 25°C
• Storage Temp.: 2-8°C
• Solubility: H2O: 100 mg/mL, clear, yellow-green
• CAS DataBase Reference: L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT(63699-78-5)
• EPA Substance Registry System: L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT(63699-78-5)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 63699-78-5(Hazardous Substances Data)

Usage

Description

L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT is a light yellow powder that serves as a synthetic substrate for gamma-glutamyltransferase (GGT). It is utilized in the determination of GGT activity, which is an essential enzyme involved in the transport of amino acids across cell membranes.

Uses

Used in Diagnostic Applications:
L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT is used as a diagnostic tool for assessing the activity of gamma-glutamyltransferase (GGT) in various clinical and research settings. The measurement of GGT activity can provide valuable information on liver function and potential liver diseases, as well as other conditions that may affect GGT levels.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT is used as a synthetic substrate for the development and testing of drugs targeting gamma-glutamyltransferase (GGT). This enzyme plays a role in various physiological processes, and its inhibition or modulation can be beneficial in treating certain conditions.
Used in Research and Development:
L-GLUTAMIC ACID GAMMA-(3-CARBOXY-4-NITROANILIDE) AMMONIUM SALT is also used in research and development for studying the mechanisms of action, regulation, and potential therapeutic applications of gamma-glutamyltransferase (GGT). This can lead to a better understanding of the enzyme's role in various biological processes and the development of novel therapeutic strategies.

InChI:InChI=1/C12H13N3O7.H3N/c13-8(12(19)20)2-4-10(16)14-6-1-3-9(15(21)22)7(5-6)11(17)18;/h1,3,5,8H,2,4,13H2,(H,14,16)(H,17,18)(H,19,20);1H3