63807-84-1

Basic information

• Product Name: Benzene, 1,3-bis(2-chloroethoxy)-
• CAS NO: 63807-84-1
• Molecular Formula: C10H12Cl2O2
• Molecular Weight: 235.11
• Mol File: 63807-84-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1,3-bis(2-chloroethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,3-bis(2-chloroethoxy)-(63807-84-1)
• EPA Substance Registry System: Benzene, 1,3-bis(2-chloroethoxy)-(63807-84-1)

Safety Data

• Hazardous Substances Data: 63807-84-1(Hazardous Substances Data)

Upstream product

• 102-40-9 1,3-bis(2-hydroxyethoxy)benzene 
• 107-04-0 1-Bromo-2-chloroethane 
• 108-46-3 recorcinol 

Downstream Products

• 79520-96-0 4,4'-[1,3-phenylenebis(oxy)]bis[2,2-dimethylbutanoic acid] 
• 854008-25-6 1,5-dibromo-2,4-bis(2-chloroethoxy)benzene 
• 854008-26-7 2,3-dihydrobenzo[1,2-b;5,4-b']difuran 
• 267-56-1 benzo[1,2-b;5,4-b']difuran 

Relevant articles and documents

A furan ring expansion approach to the synthesis of novel pyridazino-psoralen derivatives

A convenient preparation of the parent tetrahydrobenzodifuran 2 was developed from resorcinol. The oxidation of one or both furan rings of this key intermediate was accomplished with DDQ and the resulting benzodifuran was subsequently reacted with 3,6-dimethoxycarbonyl-1,2,4,5-tetrazine to afford the expected pyridazino-psoralen derivative in good yield. This simple method allowed the efficient preparation of a pyridazino-psoralen derivative with a formyl group at C-7, which was introduced by directed ortho-lithiation in the intermediate 2. An aminoalkyl side-chain was also introduced to the tetracyclic skeleton through the aldehyde functionality in a reductive amination process, which was accompanied by an unprecedented reduction of the pyridazine ring.