63918-85-4

Basic information

• Product Name: 2-(α-Methylphenethyl)aminoethanol
• Synonyms: 2-(α-Methylphenethyl)aminoethanol
• CAS NO: 63918-85-4
• Molecular Formula: C₁₁H₁₇NO
• Molecular Weight: 179.25878
• Mol File: 63918-85-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 311.8°C (rough estimate)
• Flash Point: 116.8°C
• Appearance: /
• Density: 1.0020 (rough estimate)
• Vapor Pressure: 0.000267mmHg at 25°C
• Refractive Index: 1.5320 (estimate)
• CAS DataBase Reference: 2-(α-Methylphenethyl)aminoethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(α-Methylphenethyl)aminoethanol(63918-85-4)
• EPA Substance Registry System: 2-(α-Methylphenethyl)aminoethanol(63918-85-4)

Safety Data

• Hazardous Substances Data: 63918-85-4(Hazardous Substances Data)

Usage

Type of compound

Amino alcohol

Key functional group

α-Methylphenethylamine

Commonly found in

Certain medications and dietary supplements

Potential use

Bronchodilator

Potential use

Beta-adrenergic agonist

Possible properties

Sympathomimetic

Studied for treatment of

Respiratory conditions (e.g. asthma, COPD)

Investigated for

Enhancing athletic performance

Investigated for

Promoting weight loss

Need for further research

To understand pharmacological properties and therapeutic uses

InChI:InChI=1/C11H17NO/c1-10(12-7-8-13)9-11-5-3-2-4-6-11/h2-6,10,12-13H,7-9H2,1H3

Upstream product

• 75-21-8 oxirane 
• 60-15-1 2-amino-1-phenylpropane 
• 141-43-5 ethanolamine 
• 103-79-7 1-phenyl-acetone 

Downstream Products

• 874004-18-9 2-{[2-(2-benzyl-phenoxy)-ethyl]-(1-methyl-2-phenyl-ethyl)-amino}-ethanol 
• 10429-63-7 N-(α-Methylphenethyl)-N-<2-(o-benzoylphenoxy)ethyl>-p-toluenesulfonamide 
• 40737-58-4 SKF 502 

Relevant articles and documents

Efficient preparation of secondary aminoalcohols through a Ti(IV) reductive amination procedure. Application to the synthesis and antibacterial evaluation of new 3β-N-[hydroxyalkyl]aminosteroid derivatives

An efficient method for the synthesis of various secondary aminoalcohols through a titanium(IV) isopropoxide-mediated reductive amination reaction of ketones is reported. Thus, different ketones gave the expected products in moderate to excellent yields up to 89% in numerous cases. A series of 3β-N-[hydroxyalkyl]aminosteroid derivatives were prepared according to this methodology and evaluated for their in vitro antimicrobial properties against human pathogens. All the compounds showed moderate to excellent activities against Gram-positive bacteria exhibiting similar results against Staphylococcus aureus and Streptococcus faecalis with Minimum Inhibitory Concentrations (MICs) varying from 3.12 to 25 μg/mL. No significant antibacterial activities are encountered against Gram-negative bacteria.