63931-22-6

Basic information

• Product Name: 5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine
• Synonyms: 4-Amino-5-bromo-6-chloro-2-methylthiopyrimidine;5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine;5-BroMo-6-chloro-2-Methylsulfanyl-pyriMidin-4-ylaMine;5-Bromo-6-chloro-2-(methylthio)pyrimidin-4-amine
• CAS NO: 63931-22-6
• Molecular Formula: C5H5BrClN3S
• Molecular Weight: 255
• Mol File: 63931-22-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 240-241℃
• Boiling Point: 379.8±37.0 °C(Predicted)
• Appearance: /
• Density: 1.90
• Storage Temp.: 2-8°C(protect from light)
• PKA: -0?+-.0.10(Predicted)
• CAS DataBase Reference: 5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine(63931-22-6)
• EPA Substance Registry System: 5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine(63931-22-6)

Safety Data

• Hazardous Substances Data: 63931-22-6(Hazardous Substances Data)

Usage

Description

5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine is a pyrimidine derivative chemical compound with the molecular formula C6H5BrN3ClS. It contains bromine, chlorine, nitrogen, and sulfur atoms, making it a versatile molecule for various applications.

Uses

Used in Pharmaceutical Industry:
5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine is used as an intermediate in the synthesis of pharmaceuticals for its potential therapeutic properties.
Used in Agricultural Chemicals:
5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine also serves as an intermediate in the synthesis of agricultural chemicals, contributing to the development of new products for crop protection and enhancement.
Used in Chemical Research and Development:
5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine is utilized in the field of chemical research and development, where its unique structure and properties are explored for new applications and advancements in chemical science.
Safety Note:
It is crucial to handle 5-Bromo-6-chloro-2-(methylthio)-4-pyrimidinamine with caution due to its potential hazardous effects if not managed properly. Proper safety measures should be taken during its use in any application.

Upstream product

• 1005-38-5 4-amino-6-chloro-2-methylthiopyrimidine 
• 7726-95-6 bromine 

Relevant articles and documents

1-(4-AMINO-5-BROMO-6-(1 H-PYRAZOL-1-YL)PYRIMIDIN-2-YL)-1 H-PYRAZOL-4-OL AND USE THEREOF IN THE TREATMENT OF CANCER

This invention relates to an active metabolite of 5-bromo-2,6-di(1H-pyrazol-1-yl)pyrimindin-4-amine that modulates the activity of adenosine A2a receptor. In particular, the present invention relates to pharmaceutical compositions comprising 1-(4-amino-5-bromo-6-(1H-pyrazol-1-yl)-pyrimidin-2-yl)-1H-pyrazol-4-ol, as well as processes for its preparation and its use in the treatment of cancer alone of in combination with one or more immunotherapeutic agents.