639521-01-0

Basic information

• Product Name: methyl (3β,5β,7α,12α)-7-(4-nitrophenoxycarbonyloxy)-12-hydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate
• Synonyms: methyl (3β,5β,7α,12α)-7-(4-nitrophenoxycarbonyloxy)-12-hydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate
• CAS NO: 639521-01-0
• Molecular Weight: 1029.32
• Mol File: 639521-01-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (3β,5β,7α,12α)-7-(4-nitrophenoxycarbonyloxy)-12-hydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (3β,5β,7α,12α)-7-(4-nitrophenoxycarbonyloxy)-12-hydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate(639521-01-0)
• EPA Substance Registry System: methyl (3β,5β,7α,12α)-7-(4-nitrophenoxycarbonyloxy)-12-hydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate(639521-01-0)

Safety Data

• Hazardous Substances Data: 639521-01-0(Hazardous Substances Data)

Upstream product

• 7693-46-1 4-Nitrophenyl chloroformate 
• 639520-78-8 methyl (3β,5β,7α,12α)-7,12-dihydroxy-3-{2-[{4-[(11β,17α)-17-hydroxy-3-oxo-17-prop-1-ynylestra-4,9-dien-11-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oate 

Relevant articles and documents

GLUCOCORTICOID RECEPTOR LIGANDS FOR THE TREATMENT OF METABOLIC DISORDERS

This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.