639785-75-4Relevant articles and documents
Design and Synthesis of Novel Rofecoxib Analogs as Potential Cyclooxygenase (COX-2) Inhibitors: Replacement of the Methylsulfonyl Pharmacophore by a Sulfonylazide Bioisostere
Uddin, Md. Jashim,Rao, P.N. Praveen,Knaus, Edward E.
, p. 861 - 868 (2007/10/03)
A group of rofecoxib analogs, having a sulfonylazide (SO2N 3) substituent in place of the methanesulfonyl (SO2CH 3) pharmacophore at the meta-position viz 3-(4-methyl, 4-methoxy, or 4-ethoxyphenyl)-4-(3-sulfonyl