63980-43-8

Basic information

• Product Name: 1-Benzyl-4-(4-pyridinyl) piperazine
• Synonyms: 1-Benzyl-4-(4-pyridinyl) piperazine;1-(Phenylmethyl)-4-(4-pyridinyl)-piperazine;1-(4-Pyridyl)-4-benzylpiperazine
• CAS NO: 63980-43-8
• Molecular Formula: C₁₆H₁₉N₃
• Molecular Weight: 253.34216
• Product Categories: pharmacetical
• Mol File: 63980-43-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 394.8°Cat760mmHg
• Flash Point: 192.6°C
• Appearance: /
• Density: 1.129g/cm³
• Vapor Pressure: 1.93E-06mmHg at 25°C
• Refractive Index: 1.605
• PKA: 10.73±0.10(Predicted)
• CAS DataBase Reference: 1-Benzyl-4-(4-pyridinyl) piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-4-(4-pyridinyl) piperazine(63980-43-8)
• EPA Substance Registry System: 1-Benzyl-4-(4-pyridinyl) piperazine(63980-43-8)

Safety Data

• Hazardous Substances Data: 63980-43-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H19N3/c1-2-4-15(5-3-1)14-18-10-12-19(13-11-18)16-6-8-17-9-7-16/h1-9H,10-14H2

Upstream product

• 2759-28-6 1-phenylmethylpiperazine 
• 1120-87-2 4-bromopyridin 
• 7379-35-3 4-chlorpyridine hydrochloride 
• 626-61-9 4-Chloropyridine 
• 19524-06-2 4-bromopyridine hydrochloride 

Downstream Products

• 1008-91-9 4-(piperazin-1-yl)pyridine 

Relevant articles and documents

ISOTHIAZOLE DIOXIDES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA): and the pharmaceutically acceptable salts and solvates thereof. D and E are different groups wherein one is N and the other is CR50. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, pain (e.g., acute pain, acute and chronic inflammatory pain, and neuropathic pain) using a compound of formula IA.

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

Soluble polymer-supported catalysts containing azo dyes

(equation presented) Azo benzene derivatives were incorporated into soluble polymer-bound catalysts by two different approaches. The first was to attach the dye to the polymer-bound catalysts, using the dye as an innocent spectator to study the phase preference, concentration, and recoverability of a catalyst. The second approach used an azo dye as a ligand to form an effective soluble polymer-bound Pd(II) catalyst for Heck reactions.