639858-45-0 Usage
Description
5-Amino-2,4-difluorobenzoic acid, 98% is an organic compound with the molecular formula C7H5F2NO2. It is a white crystalline solid and is commonly used as a chemical intermediate in the synthesis of various pharmaceuticals and bioactive molecules. 5-AMino-2,4-difluorobenzoic acid, 98% is characterized by its high purity (98%), which ensures minimal impurities and optimal performance in its intended applications.
Uses
Used in Pharmaceutical Industry:
5-Amino-2,4-difluorobenzoic acid, 98% is used as a key intermediate for the synthesis of dual vascular endothelial growth factor receptor-2 (VEGFR-2) and fibroblast growth factor receptor-1 (FGFR-1) inhibitors. These inhibitors play a crucial role in the development of targeted therapies for various types of cancer, as they help in blocking the signaling pathways involved in tumor growth and angiogenesis.
5-AMino-2,4-difluorobenzoic acid, 98% is particularly useful in the development of small molecule inhibitors that can effectively target both VEGFR-2 and FGFR-1, making it a valuable asset in the fight against cancer. By inhibiting these receptors, the compound can potentially limit the growth of new blood vessels that supply nutrients to the tumor, thereby starving the cancer cells and preventing their proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 639858-45-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,9,8,5 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 639858-45:
(8*6)+(7*3)+(6*9)+(5*8)+(4*5)+(3*8)+(2*4)+(1*5)=220
220 % 10 = 0
So 639858-45-0 is a valid CAS Registry Number.
639858-45-0Relevant articles and documents
Pyrrolotriazine kinase inhibitors
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Page/Page column 13, (2010/02/15)
The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-ca
Heterocyclic inhibitors of kinases
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Page/Page column 9, (2008/06/13)
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
