640292-08-6

Basic information

• Product Name: 3-Isoxazolepropanoic acid, b-hydroxy-a-methylene-5-phenyl-, methyl ester
• CAS NO: 640292-08-6
• Molecular Formula: C14H13NO4
• Molecular Weight: 259.262
• Mol File: 640292-08-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Isoxazolepropanoic acid, b-hydroxy-a-methylene-5-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoxazolepropanoic acid, b-hydroxy-a-methylene-5-phenyl-, methyl ester(640292-08-6)
• EPA Substance Registry System: 3-Isoxazolepropanoic acid, b-hydroxy-a-methylene-5-phenyl-, methyl ester(640292-08-6)

Safety Data

• Hazardous Substances Data: 640292-08-6(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 7063-99-2 ethyl 5-phenylisoxazole-3-carboxylate 
• 1619-37-0 (5-phenylisoxazol-3-yl)methanol 
• 59985-82-9 5-phenylisoxazole-3-carbaldehyde 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 1189021-32-6 methyl 5-[hydroxy-(5-phenylisoxazol-3-yl)methyl]-3-(2-nitrophenyl)-4,5-dihydroisoxazole-5-carboxylate 
• 1027474-50-5 (Z)-4-Amino-2-(4-methyl-piperazin-1-ylmethyl)-6-oxo-6-phenyl-hex-4-enoic acid methyl ester 
• 831181-92-1 2-cyclohexylaminomethyl-3-(5-phenylisoxazol-3-yl)propionic acid methyl ester 
• 1026100-59-3 (Z)-4-Amino-2-morpholin-4-ylmethyl-6-oxo-6-phenyl-hex-4-enoic acid methyl ester 
• 831182-42-4 2-(4-methylpiperazin-1-ylmethyl)-3-(5-phenylisoxazol-3-yl)acrylic acid methyl ester 
• 831181-56-7 2-(4-methylpiperazin-1-ylmethyl)-3-(5-phenylisoxazol-3-yl)propionic acid methyl ester 
• 831181-82-9 2-(benzylamino-methyl)-3-(5-phenylisoxazol-3-yl)propionic acid methyl ester 
• 831181-66-9 2-(morpholin-4-ylmethyl)-3-(5-phenylisoxazol-3-yl)propionic acid methyl ester 
• 831182-02-6 2-[(2-methylbutylamino)methyl]-3-(5-phenylisoxazol-3-yl)propionic acid methyl ester 
• 831181-22-7 2-(5-phenylisoxazol-3-ylmethyl)acrylic acid methyl ester 
• 831181-12-5 2-methyl-3-(5-phenylisoxazol-3-yl)acrylic acid methyl ester 
• 831181-42-1 (Z)-3-methyl-5-(2-oxo-2-phenylethylidene)pyrrolidin-2-one 
• 798555-63-2 4-amino-2-methyl-6-oxo-6-phenyl-hex-4-enoic acid methyl ester 
• 798555-68-7 2-methyl-3-(5-phenyl-isoxazol-3-yl)-propionic acid methyl ester 

Relevant articles and documents

Facile Baylis-Hillman Reaction of Substituted 3-Isoxazolecarbaldehydes: The Impact of a Proximal Heteroatom Within a Heterocycle on the Acceleration of the Reaction

The fast and facile Baylis-Hillman reaction in substituted 3-isoxazolecarbaldehydes confirms the impact of the proximal heteroatom within a heterocycle towards enhanced reactivity of the formyl group for this reaction.