64146-61-8

Basic information

• Product Name: Benzene, 1-(1-heptynyl)-4-methoxy-
• CAS NO: 64146-61-8
• Molecular Formula: C14H18O
• Molecular Weight: 202.296
• Mol File: 64146-61-8.mol
• Article Data: 35

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1-heptynyl)-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1-heptynyl)-4-methoxy-(64146-61-8)
• EPA Substance Registry System: Benzene, 1-(1-heptynyl)-4-methoxy-(64146-61-8)

Safety Data

• Hazardous Substances Data: 64146-61-8(Hazardous Substances Data)

Upstream product

• 628-71-7 1-Heptyne 
• 696-62-8 para-iodoanisole 
• 105826-09-3 diheptynylmagnesium 
• 64146-57-2 1-heptynylzinc chloride 
• 15719-56-9 1-heptynyltrimethylsilane 
• 627885-28-3 dimethyl-(1-heptynyl)silanol 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 627885-31-8 1-heptynyldimethylsilane 
• 5663-96-7 oct-2-ynoic acid 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 19821-84-2 1-bromohept-1-yne 
• 5720-07-0 4-methoxyphenylboronic acid 
• 3899-91-0 4-methoxyphenyl p-toluenesulfonate 
• 623-12-1 4-chloromethoxybenzene 

Downstream Products

• 1286680-10-1 methyl (2E,4E)-4-(4-methoxybenzylidene)-2-nonenoate 
• 1263054-00-7 1-(4-methoxyphenyl)-2-[2-(phenylthio)phenyl]heptan-1-one 
• 69287-13-4 1-(4-methoxyphenyl)-1-heptanone 
• 1276045-75-0 C₂₁H₂₅NO₄ 

Relevant articles and documents

Ligand-Free and Recyclable Palladium(II) Acetate Catalyzes the Decarboxylative Cross-Coupling of Alkynyl Carboxylic Acids with Arylboronic Acids in Aqueous PEG-400

A novel and ligand-free method was developed for the decarboxylative cross-coupling of alkynylcarboxylic acids with arylboronic acids. By using an environmentally friendly H 2 O-poly(ethylene glycol) (PEG-400) system as the reaction medium, a series of internal alkynes were synthesized in good yields and with remarkable selectivity. The Pd(OAc) 2-H 2 O-PEG-400 catalytic system could be used for up to three cycles without any loss of activity, demonstrating the robustness of the approach.

Photoredox/Cobalt Dual Catalysis for Visible-Light-Mediated Alkene-Alkyne Coupling

Dual photoredox transition-metal catalysis has recently emerged as a powerful tool for making synthetically challenging carbon-carbon bonds under milder reaction conditions. Herein, we report on the visible-light-mediated controlled generation of low-valent cobalt catalyst without the need for a metallic reductant. It enabled C-C bond formation via ene-yne coupling at room temperature. The generality of this dual catalysis is demonstrated via the creation of sizable molecular diversity with the accommodation of several functional groups.

Ferrocenyl bisoxazoline as an efficient non-phosphorus ligand for palladium-catalyzed copper-free Sonogashira reaction in aqueous solution

Pd(OAc)2-catalyzed Sonogashira coupling reactions of alkynes and a variety of aryl halides with 1,3-bis(5-ferrocenylisoxazoline-3-yl)benzene as an efficient non-phosphorus ligand under copper-free conditions are presented. The main advantages over previous methodologies include low catalyst loading (0.2 mol% Pd(OAc)2 and 0.4 mol% ferrocenyl bisoxazoline ligand are sufficient for these coupling reactions), less problematic reaction medium (water–dimethylformamide) and more convenient operation (no requirement for nitrogen protection).