64181-76-6 Usage
Description
[1,1'-Biphenyl]-2-ol,4'-chlorois a chemical compound derived from biphenyl, featuring a chloro group at the 4' position of one of the phenyl rings. This aromatic compound is widely utilized in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The presence of the chloro group modifies its physicochemical properties and reactivity, broadening its potential applications. It may also possess biological activities and serve as an intermediate in chemical production or a reagent in organic chemistry reactions, although further research is required to fully explore its potential.
Uses
Used in Pharmaceutical Industry:
[1,1'-Biphenyl]-2-ol,4'-chlorois used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure and reactivity contribute to the creation of novel drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, [1,1'-Biphenyl]-2-ol,4'-chlorois used as a building block for the synthesis of agrochemicals, such as pesticides and herbicides. Its properties allow for the development of more effective and targeted products for agricultural use.
Used in Organic Chemistry:
[1,1'-Biphenyl]-2-ol,4'-chloroserves as a reagent in organic chemistry reactions, facilitating the synthesis of complex organic molecules. Its versatility and reactivity make it a valuable tool in the field of organic chemistry.
Used in Chemical Production:
[1,1'-Biphenyl]-2-ol,4'-chloromay also be used as an intermediate in the production of other chemicals, leveraging its unique structure and properties to create a variety of useful compounds for various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 64181-76-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,1,8 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 64181-76:
(7*6)+(6*4)+(5*1)+(4*8)+(3*1)+(2*7)+(1*6)=126
126 % 10 = 6
So 64181-76-6 is a valid CAS Registry Number.
64181-76-6Relevant articles and documents
Strongly Directing Substituents in the Radical Arylation of Substituted Benzenes
Hofmann, Josefa,Clark, Timothy,Heinrich, Markus R.
, p. 9785 - 9791 (2016/10/31)
Although general interest in radical arylation reactions has grown rapidly in recent years, poor regioselectivities and the need to use a large excess of the radical-accepting arene have hindered their application to substituted benzenes. We now describe experimental and computational investigations into the substituent effects that lead to regioselective addition based on the recent discovery of anilines as outstanding substrates for radical arylations.
Regioselective radical arylation of anilines with arylhydrazines
Jasch, Hannelore,Scheumann, Julia,Heinrich, Markus R.
, p. 10699 - 10706 (2013/02/25)
Substituted 2-aminobiphenyls have been prepared from arylhydrazines and anilines via radical arylation reactions under simple oxidative conditions. The strong directing effect of the free and unprotonated amino functionality leads to high regioselectivities, and anilines have been shown to be significantly better aryl radical acceptors than nitrobenzenes or phenyl ethers. The methodology is also applicable to phenols, which react best as phenolates under strongly basic conditions. Finally, radical arylation reactions of anilines and anilinium salts under various conditions have for the first time demonstrated that regioselectivity can also be controlled through the rearomatization step and that the addition of an aryl radical to a substituted benzene might even be reversible.