64260-76-0

Basic information

• Product Name: Benzo[b]thiophene, 5-bromo-2,3-dihydro-, 1,1-dioxide
• CAS NO: 64260-76-0
• Molecular Formula: C8H7BrO2S
• Molecular Weight: 247.112
• Mol File: 64260-76-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 404.4±45.0 °C(Predicted)
• Density: 1.749±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzo[b]thiophene, 5-bromo-2,3-dihydro-, 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzo[b]thiophene, 5-bromo-2,3-dihydro-, 1,1-dioxide(64260-76-0)
• EPA Substance Registry System: Benzo[b]thiophene, 5-bromo-2,3-dihydro-, 1,1-dioxide(64260-76-0)

Safety Data

• Hazardous Substances Data: 64260-76-0(Hazardous Substances Data)

Upstream product

• 41553-54-2 5-bromo-2,3-dihydrobenzo[b]thiophene 
• 19492-87-6 5-bromo-benzo[b]thiophene 1,1-dioxide 
• 95-15-8 Benzo[b]thiophene 
• 4565-32-6 2,3-dihydrobenzo(b)thiophene 
• 4923-87-9 5-bromobenzo[b]thiophene 

Relevant articles and documents

20-HETE FORMATION INHIBITORS

This disclosure provides novel heterocyclic compounds and methods for inhibiting the enzyme CYP4. Further disclosed methods include: a method of inhibiting the biosynthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) in a subject in need thereof and a method of producing neuroprotection and decreased brain damage by preventing cerebral microvascular blood flow impairment and anti-oxidant mechanisms in a subject experiencing or having experienced an ischemic event.

COMPOUNDS AS MODULATORS OF ROR GAMMA

The present invention encompasses compounds of the formula (I) wherein the variables are defined herein which are suitable for the modulation of RORγ and the treatment of diseases related to the modulation of RORγ. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.

ACYCLIC CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.