64418-88-8Relevant articles and documents
Total Synthesis of Divergolides E and H
Caplan, Scott M.,Floreancig, Paul E.
, p. 15866 - 15870 (2018/11/10)
This manuscript describes the first total syntheses of divergolides E and H. The route employs a telescoped hetero-Diels–Alder and oxidative carbon–hydrogen bond cleavage as an entry into the central bridged bicyclic acetal unit. Additional key steps of the highly convergent route include a desymmetrizing epoxidation, a chelation-controlled alkenylzinc addition, an amide formation between a hindered aniline and an acylating agent that is prone to ketene formation, and a challenging macrolactonization.
Fischer's base as a protecting group: Protection and deprotection of 2- hydroxybenzaldehydes
Cho, Young Jin,Lee, Seung Hwan,Bae, Jong Woo,Pyun, Hyung-Jung,Yoon, Cheol Min
, p. 3915 - 3917 (2007/10/03)
The hydroxyl and aldehyde groups of 2-hydroxybenzaldehydes were protected by the reaction with Fischer's base and deprotected by the ozonolysis in methanol at -78°C to give the corresponding 2- hydroxybenzaldehydes in good to high yields. (C) 2000 Elsevier Science Ltd.