64450-21-1

Basic information

• Product Name: 2-Propanone, 1-[(4-fluorophenyl)methylamino]-
• CAS NO: 64450-21-1
• Molecular Formula: C10H12FNO
• Molecular Weight: 181.21
• Mol File: 64450-21-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propanone, 1-[(4-fluorophenyl)methylamino]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanone, 1-[(4-fluorophenyl)methylamino]-(64450-21-1)
• EPA Substance Registry System: 2-Propanone, 1-[(4-fluorophenyl)methylamino]-(64450-21-1)

Safety Data

• Hazardous Substances Data: 64450-21-1(Hazardous Substances Data)

Upstream product

• 459-59-6 4-fluoro-N-methylaniline 
• 56-81-5 glycerol 
• 78-95-5 chloroacetone 

Downstream Products

• 81580-22-5 5-(2-{2-[(4-Fluoro-phenyl)-methyl-amino]-1-methyl-ethylamino}-1-hydroxy-ethyl)-2-hydroxy-benzamide 

Relevant articles and documents

Ru-Catalyzed Switchable N-Hydroxyethylation and N-Acetonylation with Crude Glycerol

Highly efficient Ru-catalyzed selective C?C or C?O bond cleavage of polyols (e.g., crude glycerol) for N-hydroxyethylation or N-acetonylation of amines was achieved through the hydrogen-borrowing approach. A variety of amines were transformed to the desired amino alcohols/ketones in moderate-to-excellent yields, opening up new avenues for generation of oxygenated pharmaceuticals and fine chemicals from renewable raw materials. The use of new redox-active catalysts containing bisphosphine/thienylmethylamine ligands allows this hydrogen-borrowing system to be operated selectively under both basic and acidic conditions.