64486-19-7 Usage
Description
[6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[[2-(chloroacetamido)thiazol-4-yl](methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is a complex antibiotic derivative with a bicyclic ring system and various functional groups, including a thiazole ring, an acetoxymethyl group, an oxo group, a carboxylic acid group, and a chloroacetamido group. Its intricate molecular structure suggests its potential as a potent antibiotic.
Uses
Used in Pharmaceutical Industry:
[6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[[2-(chloroacetamido)thiazol-4-yl](methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is used as an antibiotic for treating bacterial infections. Its complex molecular structure and multiple functional groups contribute to its potency and effectiveness against a wide range of bacteria.
Used in Research and Development:
In the field of scientific research, this compound is used as a subject for studying the structure-activity relationship of antibiotics. Its unique features and functional groups provide valuable insights into the development of new and improved antimicrobial agents.
Used in Drug Resistance Studies:
[6R-[6alpha,7beta(Z)]]-3-(acetoxymethyl)-7-[[2-(chloroacetamido)thiazol-4-yl](methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid can be employed in research aimed at understanding and combating antibiotic resistance. Its complex structure may offer new avenues for overcoming resistance mechanisms in bacteria.
Used in Drug Delivery Systems:
Similar to gallotannin, this complex antibiotic derivative could potentially be incorporated into novel drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. The development of such systems could improve the efficacy of the compound and reduce the likelihood of resistance development.
Check Digit Verification of cas no
The CAS Registry Mumber 64486-19-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,4,8 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 64486-19:
(7*6)+(6*4)+(5*4)+(4*8)+(3*6)+(2*1)+(1*9)=147
147 % 10 = 7
So 64486-19-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H18ClN5O8S2/c1-7(25)32-4-8-5-33-16-12(15(28)24(16)13(8)17(29)30)22-14(27)11(23-31-2)9-6-34-18(20-9)21-10(26)3-19/h6,12,16H,3-5H2,1-2H3,(H,22,27)(H,29,30)(H,20,21,26)/b23-11+/t12-,16-/m1/s1
64486-19-7Relevant articles and documents
Process for the production of cefotaxime sodium
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Page/Page column 4, (2008/06/13)
A process for the production of 7-[2-(2-amino-4-thiazolyl)-2-syn-methoxyimino-acetamido]-3-acetoxymethyl-3-cephem-4-carboxylic acid (Cefotaxime) in aqueous isopropyl alcohol is provided. The synthesis provides the product in greater than 99 % HPLC purity.
Cephalosporin derivatives
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, (2008/06/13)
The present invention relates to novel cephalosporin derivatives, processes for preparing thereof, compositions for preventing and/or treating infectious diseases which comprise the novel cephalosporin derivatives as active components, and the intermediate compounds in the synthesis of cephalosporin derivatives and processes for producing thereof. The novel cephalosporin derivatives according to the present invention contain condensed heterocyclic groups, particularly a triazolopyrimidine ring or a thiadiazolopyrimidine ring as substituents at the 3-position of the cephem skeleton, and a hydroxyimino, an alkyloxyimino or an acyloxyimino moiety as substituents at the 7-position of the cephem skeleton. The compounds of the present invention containing the aforementioned substituents have a strong antibacterial activity against gram-negative bacteria and also against gram-positive bacteria including methicillin-resistant Staphylococcus aureus. These compounds are extremely useful for the treatment of infectious diseases.
